Improving the appearance of cesarean section scars
Official title: Post-Operative Cosmesis and Skin Closure Methods After Cesarean Section
Run by Wake Forest University Health Sciences · NCT06412978 · Data updated 2026-11-12
This study is testing two different ways to close the skin after a cesarean delivery to see which one makes the scar look better.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 44 Years |
| Sex | Women only |
| Enrollment | 52 (estimated) |
| Sponsor | Wake Forest University Health Sciences Academic / other |
| Locations | 1 site (Winston-Salem, North Carolina) |
| Status | Recruiting |
| Started | September 5, 2024 |
| Main results expected | April 2027 |
| Study ends | April 2027 |
| Registry record updated | October 23, 2026 |
| Trial ID | NCT06412978 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are women aged 18-44 who are scheduled for a cesarean section and can receive neuraxial analgesia.
✕Probably not a fit
Patients who may not benefit include those with a BMI over 40, those with prior cesarean deliveries, or those with certain medical conditions like connective tissue disorders.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates two different techniques for closing the skin after a cesarean delivery to determine which method results in better cosmetic outcomes. The techniques being compared are absorbable subcuticular polyglycolic acid staples and subcuticular polyglecaprone sutures. Given the high prevalence of cesarean deliveries in the U.S., optimizing surgical techniques could significantly impact patient satisfaction and recovery. The study is randomized, ensuring that participants are assigned to one of the two closure methods in a controlled manner.
Why it matters
Potential benefit: If successful, this study could lead to improved cosmetic outcomes for women undergoing cesarean deliveries.
How similar studies have gone: While there is ongoing interest in optimizing cesarean delivery techniques, this specific comparison of closure methods is relatively novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18-44 * Any race * Any parity * Scheduled cesarean section * Neuraxial analgesia Exclusion Criteria: * Non-English Speaking * Incarcerated * Maternal Connective Tissue Disorder * Systemic maternal steroid use * Three prior cesarean deliveries * Body Mass Index (BMI) \>40
Where it's running
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Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States Recruiting
Study contacts
- Principal investigator: Joshua F Nitsche, MD — Wake Forest University Health Sciences
- Study coordinator: Christina Tulbert
- Email: Christina.Tulbert@Advocatehealth.org
- Phone: 336.716.2383
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Dexmedetomidine or Clonidine added to spinal anesthesia for cesarean delivery
This study tests whether adding dexmedetomidine or clonidine to spinal anesthesia for cesarean delivery improves intraoperative comfort and analgesia.
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Cesarean Anesthesia Blood Gas
This study tests and compares blood gas parameters in moms and babies when cesarean deliveries are done with spinal vs general anesthesia.
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Buprenorphine vs morphine for pain control after cesarean delivery
This study tests whether intrathecal buprenorphine provides better postcesarean pain relief than morphine for women undergoing a planned cesarean delivery.
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Restrained vs Gripping Wrist Restraints for Cesarean Delivery
This study tests whether a soft wrist-level gripping restraint reduces anxiety for adults having an elective cesarean delivery under spinal or combined spinal-epidural anesthesia.
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Pupil light reflex to predict low blood pressure after spinal anesthesia in cesarean deliveries
Doctors want to see if a quick eye-pupil test done before spinal anesthesia can predict who might develop low blood pressure after a cesarean delivery.
-
Arm versus ankle mean arterial pressure during elective cesarean delivery
This study will see if a blood pressure cuff on the ankle gives similar mean arterial pressure readings to a standard arm cuff in pregnant people having a planned C-section under spinal anesthesia.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.