Improving suicide prevention strategies for teens
Official title: Advancing Suicide Intervention Strategies for Teens During High Risk Periods
Run by Seattle Children's Hospital · NCT05078970 · Data updated 2026-11-12
This study is testing two new ways to help teens aged 11-17 who are at risk of suicide to see if they work better than regular care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 11 Years to 17 Years |
| Sex | All |
| Enrollment | 306 (estimated) |
| Sponsor | Seattle Children's Hospital Academic / other |
| Locations | 2 sites (Columbus, Ohio and 1 other locations) |
| Status | Recruiting |
| Started | August 11, 2022 |
| Main results expected | January 31, 2027 |
| Study ends | January 31, 2027 |
| Registry record updated | November 14, 2025 |
| Trial ID | NCT05078970 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adolescents aged 11-17 who have endorsed suicidal thoughts or behaviors and have been admitted to acute care due to suicidality.
✕Probably not a fit
Patients with psychosis, intellectual disabilities, autism spectrum disorder, or unstable eating disorders may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of two interventions, Safety Planning Intervention with follow-up (SPI+) and Collaborative Assessment and Management of Suicidality (CAMS), compared to usual care for adolescents at risk of suicide. Participants, aged 11-17, who have experienced suicidal ideation or behavior, will receive assessments at multiple time points to track their progress and the impact of the interventions. The study aims to identify the mechanisms behind the therapeutic effects and determine which factors influence treatment outcomes. Both adolescents and their parents will be involved in the research process.
Why it matters
Potential benefit: If successful, this study could lead to more effective suicide prevention strategies for adolescents, potentially reducing suicide attempts and ideation.
How similar studies have gone: Other studies have shown promise in similar intervention approaches, suggesting potential for success in this area.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Provision of signed and dated informed consent form 2. Youth, aged 11-17 3. Endorse suicidal ideation and/or behavior 4. Admitted to acute care (emergency, inpatient medical or inpatient psychiatric) due to suicidality Exclusion Criteria: 1. Presence of psychosis, intellectual disability, autism spectrum disorder, eating disorder with unstable vitals 2. Limited English proficiency that would interfere with the ability to complete study assessments
Where it's running
-
Nationwide Children's
Columbus, Ohio, United States Recruiting -
Seattle Children's
Seattle, Washington, United States Recruiting
Study contacts
- Principal investigator: Molly Adrian — Seattle Childrens
- Study coordinator: Molly Adrian
- Email: molly.adrian@seattlechildrens.org
- Phone: 206-987-7183
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Intensive Crisis Intervention for teens with suicidal thoughts or behaviors
This project will try a brief, family-focused Intensive Crisis Intervention to see if it helps 12–17-year-olds with suicidal thoughts or recent attempts reduce suicidal behavior and avoid inpatient psychiatric care.
-
Dialectical behavior therapy for adolescents with self-harm and suicidal behavior
This study is testing if Dialectical Behavior Therapy can help teenagers aged 13-18 who self-harm and have suicidal thoughts feel better and reduce their harmful behaviors over 20 weeks.
-
Reducing self-injurious thoughts and behaviors in adolescents during and after hospitalization
This study is testing a new way to help teenagers aged 12-19 who have self-harm thoughts and behaviors feel better during and after their hospital stay using an app on iPads and smartphones.
-
Testing a mobile app to help prevent suicide
This study is testing a new mobile app designed to help young adults who have had suicidal thoughts or behaviors in the past month to see if it can prevent suicide.
-
Multi-layered digital monitoring and pharmacogenomics to prevent suicide in adults with depression
This study tests whether a digital monitoring system, a digital safety plan, and pharmacogenetic-guided care can reduce suicide re-attempts in adults with depression.
-
Rapid relief of suicidal thoughts with ketamine and a crisis plan in the emergency department
This study tests whether a single intramuscular dose of ketamine plus a brief Crisis Response Plan helps reduce suicidal thoughts in ED patients who are likely to be admitted.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.