Improving stroke recovery through error-based learning in arm exercises
Error-enhanced Learning & Recovery in 2 & 3 Dimensions
This study is testing if helping stroke patients learn from their mistakes during arm exercises can improve their recovery and movement using special technology.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Shirley Ryan AbilityLab Academic / other |
| Locations | 3 sites (Chicago, Illinois and 2 other locations) |
| Trial ID | NCT05180786 on ClinicalTrials.gov |
What this trial studies
This study evaluates how errors made by stroke patients during upper extremity exercises can lead to improved motor recovery. Participants will engage in customized reaching exercises tailored to their specific error patterns, utilizing advanced robotics and virtual reality technology. The goal is to enhance neuroplasticity and motor re-learning by understanding the relationship between errors and performance improvement. The study aims to lay the groundwork for future randomized controlled trials by testing this innovative approach to rehabilitation.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are at least 8 months post-stroke with hemiparesis and some movement capability in their shoulder and elbow.
Not a fit: Patients with bilateral paresis, severe cognitive or sensory deficits, or those unable to provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly enhance recovery outcomes for stroke patients by personalizing rehabilitation exercises.
How similar studies have performed: While the concept of error-based learning in rehabilitation is gaining traction, this specific approach utilizing robotics and personalized error analysis is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. 18 years of age or older 2. Chronic stroke (8+ months post stroke event) with primary motor cortex involvement 3. Hemiparesis 4. Some degree of both shoulder and elbow movement capability Exclusion Criteria: 1. Bilateral paresis 2. Severe tactile deficits using the Two-Point Discrimination Test (participant must detect\<11mm) 3. Severe proprioceptive deficits 4. Severe spasticity (Modified Ashworth \>3) preventing movement 5. Aphasia, cognitive impairment, or affective dysfunction that would influence the ability to perform the experiment 6. Visual deficits, and hemispatial neglect that would prevent the subjects from seeing the targets. 7. Inability to provide an informed consent 8. severe current medical problems 9. diffuse/multiple lesion sites or multiple stroke events 10. Inability to attain and maintain testing positions 11. Botox injection to the affected upper extremity within the previous 4 months 12. Concurrent participation in upper extremity rehabilitation either as part of a research intervention protocol or a prescribed therapy 13. Participation in previous, similar robotics intervention study 14. Other neurological issues None of the following special populations will be included in this research study: * Adults unable to consent * Individuals who are not yet adults (infants, children, teenagers) * Pregnant women * Prisoners * Vulnerable Populations
Where this trial is running
Chicago, Illinois and 2 other locations
- Shirley Ryan AbilityLab (Healthy Participants) — Chicago, Illinois, United States (Recruiting)
- Shirley Ryan AbilityLab — Chicago, Illinois, United States (Recruiting)
- Shirley Ryan AbilityLab — Chicago, Illinois, United States (Recruiting)
Study contacts
- Principal investigator: James Patton, PhD — Shirley Ryan AbilityLab
- Study coordinator: Courtney Celian
- Email: ccelian@sralab.org
- Phone: 3122381560
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.