Clinical trial Recruiting at 1 site Interventional Ages 18 to 45 Men only

Improving sperm quality with prenatal supplements

Official title: A Three Month Course of Power Prenatal Supplements to Improve Sperm Quality in Male-factor Infertility Patients

Run by The Bird and Be Co Inc · NCT05410782 · Data updated 2026-11-12

This study is testing whether a 90-day course of a special prenatal supplement can improve sperm quality in men aged 18-45 who are having trouble with infertility.

Quick facts

Study typeInterventional
Ages18 Years to 45 Years
SexMen only
Enrollment50 (estimated)
SponsorThe Bird and Be Co Inc
Industry-sponsored
Locations1 site (Mississauga, Ontario)
StatusRecruiting
StartedNovember 1, 2023
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedApril 8, 2025
Trial IDNCT05410782 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are males aged 18-45 who have experienced infertility and have a recent abnormal semen analysis indicating low sperm count, motility, or morphology.

Probably not a fit

Patients with diagnosed varicocele or those currently taking antioxidant supplements may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of a 90-day course of the 'Power Prenatal for Sperm' supplement on sperm quality in men experiencing infertility. Male participants aged 18-45 with recent abnormal semen analysis results will be recruited from the Reproductive Care Centre. The primary outcome will focus on progressive motility, with semen analyses conducted before and after the intervention to assess changes. The study aims to determine if the supplement can significantly improve sperm parameters, thereby addressing male factor infertility.

Why it matters

Potential benefit: If successful, this intervention could enhance sperm quality and improve fertility outcomes for men struggling with infertility.

How similar studies have gone: While the effects of supplements on sperm quality are debated, this approach is relatively novel and has not been extensively tested in this specific context.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male
* Age 18-45 years old
* Experiencing infertility
* A recent semen analysis confirming low count, motility or morphology (at least 1 of 3) - within last 3 months

  1. Low concentration: \< 15 Million / mL
  2. Low Motility: Progessive Motility \< 30%
  3. Morphology: Strict criteria: Normal forms \< 4% Reference: WHO 2020 6th edition: https://www.who.int/publications/i/item/9789240030787

Exclusion Criteria:

* No diagnosed varicocele
* Younger than 18 years old
* Older than 45 years old
* Currently taking any form of antioxidant supplements(in last 3 months) besides a general multivitamin

Where it's running

  • Reproductive Care Centre
    Mississauga, Ontario, Canada
    Recruiting

Study contacts

  • Principal investigator: Dan Nayot, BSc, MSc, MD — The Bird and Be Co
  • Study coordinator: Dan Nayot, Bsc, MSc, MD
  • Email: dan@birdandbe.com
  • Phone: 4166163334

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.