Improving soft tissue around dental implants using two methods
Evaluation of Xenogeneic Collagen Matrix Versus Connective Tissue Graft to Enhance Soft Tissue Profile Around Single Dental Implants in the Aesthetic Zone
NA · Damascus University · NCT06837688
This study is testing two different methods to see which one works better for improving the soft tissue around dental implants in the front of the mouth for adults with a missing tooth.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Damascus University (other) |
| Locations | 1 site (Damascus) |
| Trial ID | NCT06837688 on ClinicalTrials.gov |
What this trial studies
This clinical trial compares the effectiveness of two techniques for enhancing soft tissue around dental implants in the aesthetic zone of the anterior maxilla. It involves 30 adult patients with a single missing tooth who will be randomly assigned to receive either an autogenous connective tissue graft or a xenogeneic collagen matrix. The study employs a fully digital workflow for precise implant planning and placement, utilizing advanced imaging and CAD/CAM technology. The primary goal is to assess the increase in buccal soft tissue thickness following the procedures.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 or older with a single missing tooth in the aesthetic zone and sufficient bone and keratinized tissue.
Not a fit: Patients with systemic diseases, smoking habits, periodontal disease, or those requiring additional bone augmentation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a less invasive and effective method for improving soft tissue aesthetics around dental implants.
How similar studies have performed: Previous studies have shown promising results with similar soft tissue augmentation techniques, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 18 years or older. * Good oral hygiene, defined as full-mouth plaque score ≤25%. * Having a single missing tooth in the aesthetic zone of the maxilla. * Tooth extraction occurred at least 3 months prior to enrolment. * Having adequate bone volume for implant placement (bucco-palatal bone dimension of at least 6 mm). * Having at least 5 mm of keratinized tissue width at the implant site. Exclusion Criteria: * Systemic diseases. * Smoking. * Periodontal disease. * Untreated caries lesions. * Need for horizontal bone augmentation at the time of implant placement.
Where this trial is running
Damascus
- Damascus University — Damascus, Syria (RECRUITING)
Study contacts
- Principal investigator: Ali Omair, DDS — Damarcus University
- Study coordinator: Ali Omair, DDS
- Email: ali.omair.formal@gmail.com
- Phone: +963992964458
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Missing Teeth, Peri-implant soft tissue augmentation, Xenogeneic collagen matrix, Connective tissue graft