Improving Sit-to-Stand Ability in ICU Survivors

Effect of Sit-to-Stand Intervention in the Intensive Care Unit Survivors: A Randomized Controlled Trial

NA · National Taiwan University Hospital · NCT04640441

This study is testing a new sit-to-stand care program to see if it helps ICU survivors, aged 20 and older, regain their ability to stand up and improve their overall physical function.

Quick facts

PhaseNA
Study typeInterventional
Enrollment273 (estimated)
Ages20 Years and up
SexAll
SponsorNational Taiwan University Hospital (other)
Locations1 site (Taipei, National Taiwan University Hospital)
Trial IDNCT04640441 on ClinicalTrials.gov

What this trial studies

This research aims to enhance the sit-to-stand ability of patients who have survived intensive care unit (ICU) treatment. It involves a randomized controlled trial where participants, aged 20 and older, who are unable to perform sit-to-stand after ICU discharge, will receive either standard care or an additional sit-to-stand care protocol for two weeks. The study will evaluate various functional outcomes over the course of one year, including rates of bed-bound status and mortality. The goal is to determine the effectiveness of this intervention in improving physical function and independence in daily activities.

Who should consider this trial

Good fit: Ideal candidates are adults aged 20 and older who have been in the ICU for more than two days and are unable to sit-to-stand at the time of discharge.

Not a fit: Patients who were bedridden prior to hospitalization or have severe comorbidities affecting mobility may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the physical function and quality of life for ICU survivors.

How similar studies have performed: Other studies have shown promising results with similar interventions aimed at improving mobility in ICU survivors, indicating potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 20 years or older.
* Admitted for ICU treatment \> 2 days.
* Unable to sit-to-stand by ICU discharge.

Exclusion Criteria:

* Unable to follow command.
* Bedridden before index hospitalization.
* Ventilator dependent after ICU discharge .
* Received palliative care.
* Co-morbidities of the trunk or lower limbs unable to ambulate due to neuromuscular or musculoskeletal etiology (e.g. CVA, spinal cord injury, amputation or fracture of lower limb).
* Placed on droplet or contact precausion (e.g. Open TB, SARS, COVID-19 )

Where this trial is running

Taipei, National Taiwan University Hospital

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Unable to Sit-to-stand, ICU Survivor, Sit-to-stand, Functional decline, Intensive care units, Nursing intervention, Randomized controlled trial

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.