Improving safety and accuracy of radial artery catheterization using ultrasound guidance

Clinical Research Plan for the Safety and Accuracy of Ultrasound-guided Radial Artery

This study is testing if using ultrasound can make it safer and easier for doctors to insert catheters into the radial artery for surgical patients.

Quick facts

• Phase: Not applicable
• Study type: Interventional
• Enrollment: 100 (estimated)
• Ages: 18 Years to 65 Years
• Sex: All
• Sponsor: Nanjing First Hospital, Nanjing Medical University (Academic / other)
• Locations: 1 site (Nanjing, Jiangsu)
• Trial ID: NCT06345131 on ClinicalTrials.gov

What this trial studies

This clinical research focuses on enhancing the safety and accuracy of radial artery puncture catheterization in surgical patients by utilizing ultrasound technology. The study measures anatomical parameters of the radial artery and radial nerve in the forearm to identify the optimal puncture locations. A total of 100 surgical patients will be included, who will be randomly assigned to different groups based on the puncture site. The aim is to reduce the number of punctures and complications associated with the procedure.

Who should consider this trial

Good fit: Ideal candidates are surgical patients aged 18-65 who are planning to undergo general anesthesia and invasive arterial blood pressure monitoring.

Not a fit: Patients with peripheral vascular diseases, local skin infections, or those unable to cooperate with ultrasound assessments may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to safer and more accurate catheterization procedures for surgical patients.

How similar studies have performed: While the use of ultrasound in vascular access is established, this specific approach to optimizing radial artery catheterization is novel and has not been extensively tested.

Eligibility criteria

Inclusion Criteria:

1. Selected surgical patients planning to undergo general anesthesia and invasive arterial blood pressure monitoring
2. ASA grading I to II
3. Age 18-65
4. Agree to participate in this clinical study and sign an informed consent form

Exclusion Criteria:

1. Patients with positive or suspected positive Allen test
2. Peripheral vascular diseases
3. Coronary artery related diseases
4. Local skin infections, ulcers, scars, and surgical history
5. Shock patients or receiving cardiac stimulants, vasoconstrictors, etc
6. Peripheral nerve injury, anatomical abnormalities, and neurological dysfunction
7. Passive upper limb position, unable to cooperate in completing ultrasound assessment

Where this trial is running

Nanjing, Jiangsu

• Nanjing First Hospital — Nanjing, Jiangsu, China (Recruiting)

Study contacts

• Study coordinator: Han Liu, MD

Conditions Surgical Patients; Ultrasound guidance; Radial artery