Improving results of outpatient endometrial biopsies

Outpatient Endometrial Biopsy Results; a Quality Improvement Project.

Observational Cairo University · NCT06694246

This study is trying to find ways to improve the success of outpatient endometrial biopsies for women by looking at what causes poor sample results and making changes to help get better outcomes.

Quick facts

Study typeObservational
Enrollment400 (estimated)
SexFemale
SponsorCairo University Academic / other
Locations1 site (Kuwait, Al Ahmadi)
Trial IDNCT06694246 on ClinicalTrials.gov

What this trial studies

This observational study focuses on enhancing the outcomes of outpatient endometrial biopsies performed using the Pipelle device, which is crucial for diagnosing endometrial cancer. The study will identify factors contributing to insufficient sample rates, which can range from 5-23%, and implement strategies to address these issues. Following the interventions, a re-audit of biopsy results will be conducted after six months to assess improvements. The study will take place at Adan Hospital in Kuwait, involving patients undergoing biopsies during a specified timeframe.

Who should consider this trial

Good fit: Ideal candidates include women undergoing outpatient endometrial biopsy due to abnormal vaginal bleeding.

Not a fit: Patients who are unable to provide samples due to physical conditions, anxiety, or severe bleeding may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more accurate diagnoses of endometrial cancer, improving patient outcomes.

How similar studies have performed: While the approach of improving biopsy techniques is common, the specific focus on addressing insufficient sample rates in this context is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients undergoing outpatient endometrial biopsy in the specified time interval (11/2024- 4/2025) will be included.

Exclusion Criteria:

* Could not obtain the sample due to patient physicals, anxiety (patient decline), cervical stenosis, or severe bleeding

Where this trial is running

Kuwait, Al Ahmadi

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HistopathologyScreening ToolTechniquesPipelleEndometrial biopsyhistopathologyendometrial samplingscreening
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.