Improving rehabilitation for lower limb trauma
Official title: Improved Training Method for Advanced Rehabilitation of Warfighters With Lower Extremity Trauma
Run by Mayo Clinic · NCT05225792 · Data updated 2026-11-12
This study is testing a new balance training program to see if it helps active duty service members and veterans with lower limb injuries recover better and avoid falls.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Rochester, Minnesota) |
| Status | Recruiting |
| Started | January 8, 2024 |
| Main results expected | April 1, 2027 |
| Study ends | September 30, 2027 |
| Registry record updated | March 19, 2026 |
| Trial ID | NCT05225792 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are active duty service members and retired veterans with lower limb trauma who are enrolled in conventional rehabilitation.
✕Probably not a fit
Patients with excessive pain or neuromuscular problems that prevent them from participating in the test protocol may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the effectiveness of an advanced balance perturbation training program designed to enhance rehabilitation for individuals with lower limb trauma. The program focuses on increasing weight-bearing strategies on prosthetic or injured limbs to help reduce the risk of stumbles and falls. Participants will undergo various assessments, including the Promis Physical Function Questionnaire and specific walking tests, while enrolled in conventional rehabilitation at military treatment centers. The study targets active duty service members and veterans with specific types of lower limb injuries.
Why it matters
Potential benefit: If successful, this approach could significantly improve rehabilitation outcomes and reduce fall risks for patients with lower limb trauma.
How similar studies have gone: Other studies have shown promise in using advanced rehabilitation techniques for similar conditions, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Research participants will be eligible active duty service members and retired veterans. * Having lower limb trauma (transtibial and transfemoral amputations, bilateral amputations, and limb salvage). * Are enrolled in conventional rehabilitation at the participating military treatment centers. * Subjects with dysvascular disease will be excluded because compromised lower limb somatosensation and circulation are independently linked with poor postural stability and a history of frequent falls. * For subjects with amputations, the individual must be a community ambulator (i.e., K-Level 3 or 4). * For subjects with limb salvage, they will need to have an IDEO and be entered into the Return-to-Run training program. Exclusion Criteria: \- Subjects must not have excessive pain or other neuromuscular problems that preclude them from performing the test protocol.
Where it's running
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Mayo Clinic in Rochester
Rochester, Minnesota, United States Recruiting
Study contacts
- Principal investigator: Kenton Kaufman, PhD — Mayo Clinic
- Study coordinator: Christine Huyber, CCRP
- Email: Huyber.Christine@mayo.edu
- Phone: (507) 266-0984
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.