Improving recovery after thyroid surgery using advanced ventilation techniques

Pressure Supporting Ventilation and Electroencephalography-guided Extubation for Free of Unwanted compLications (PEACEFUL): a Randomised Controlled Trial

NA · Gangnam Severance Hospital · NCT06165562

This study is testing if using advanced breathing techniques during and after thyroid surgery can help younger adults recover better and avoid complications compared to standard methods.

Quick facts

PhaseNA
Study typeInterventional
Enrollment120 (estimated)
Ages19 Years to 39 Years
SexAll
SponsorGangnam Severance Hospital (other)
Locations1 site (Seoul)
Trial IDNCT06165562 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of pressure supporting ventilation combined with EEG-guided emergence in reducing airway complications following thyroid surgery. Adult patients under 40 years old will be randomly assigned to either the intervention group, which utilizes advanced ventilation and EEG monitoring for extubation, or the control group, which follows conventional extubation practices. The primary outcomes include the incidence of emergence coughing and the lowest oxygen saturation levels post-surgery, while secondary outcomes assess various recovery metrics and patient satisfaction. The goal is to determine if the new approach leads to better recovery outcomes compared to standard methods.

Who should consider this trial

Good fit: Ideal candidates are adult patients under 40 years scheduled for thyroid surgery.

Not a fit: Patients with conditions such as sleep apnea, obesity, or those undergoing more complex surgeries like radical neck dissection may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce airway complications and improve recovery experiences for patients undergoing thyroid surgery.

How similar studies have performed: While similar approaches have been explored, this specific combination of techniques is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients aged under 40 years who are scheduled to undergo thyroid surgery.

Exclusion Criteria:

* Patients scheduled for radical neck dissection
* Patients scheduled for lymph node biopsy
* Patients with an anticipated difficult airway
* Patients experiencing difficulty during intubation
* Patients with a fasting time not meeting institutional policy
* Patients with a body mass index (BMI) greater than 30 kg/m²
* Patients with sleep apnea
* Pregnant or breastfeeding women
* Patients unable to communicate

Where this trial is running

Seoul

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Thyroid Surgery

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.