Improving recovery after emergency surgery for acute abdomen
Safety and Efficacy of Enhanced Recovery After Surgery (ERAS) in Patients Undergoing Emergency Laparotomy: A Single Center Randomized Controlled Trial
This study is testing if a special recovery plan can help people recover faster and feel better after emergency surgery for stomach issues compared to standard care.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 160 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Tianjin Medical University Academic / other |
| Locations | 1 site (Tianjin, Tianjin) |
| Trial ID | NCT06182488 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the safety and effectiveness of Enhanced Recovery After Surgery (ERAS) protocols compared to conventional care in patients undergoing emergency laparotomy. Participants will be randomly assigned to either the ERAS group or the conventional care group, receiving tailored perioperative management. The study will assess outcomes such as pain levels, recovery speed, and hospital stay duration to determine the efficacy of ERAS in emergency surgical settings, which have been under-researched. By implementing ERAS strategies, the trial seeks to enhance recovery for patients facing acute abdominal conditions.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-70 who require emergency surgery for acute abdominal conditions within 6 hours of diagnosis.
Not a fit: Patients with psychiatric disorders, severe sepsis, or those requiring complex surgical procedures beyond the specified criteria may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to faster recovery times and reduced hospital stays for patients undergoing emergency surgery.
How similar studies have performed: While ERAS protocols have shown success in elective surgeries, their application in emergency surgery is less explored, making this approach relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients between the ages 18-70, * Patients who completed the preoperative examination and preoperative diagnosis within 4 hours after admission for acute abdomen diseases, * Required emergency surgery within 6 hours from surgeon encounter. Exclusion Criteria: * Patients who refused to be enrolled in this study; * Patients with any psychiatric or neurological disorders; * Pseptic shock at admission; * Duration of symptoms more than five days; * Patients with contraindications to the placement of lumbar epidural catheters, such as coagulation disorders, severe sepsis, etc.; * Presence of preoperative factors affecting wound healing (e.g. long-term steroid use); * Patients with extra-abdominal injuries or terminal malignancy, or patients requiring damage control surgery; * Patients found intraoperatively to require any procedure other than splenectomy, partial hepatectomy or liver repair, bowel resection and anastomosis, laparoscopic cholecystectomy and appendectomy, and gastrointestinal perforation repair.
Where this trial is running
Tianjin, Tianjin
- Tianjin Hospital — Tianjin, Tianjin, China (Recruiting)
Study contacts
- Study coordinator: Jianing Lu, MD
- Email: lujianing2006@163.com
- Phone: 86-022-60910136
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.