Improving recovery after elective abdominal surgery
Randomized, Embedded, Multifactorial Adaptive Platform for Perioperative Medicine at UPMC (UPMC REMAP): Core Protocol - Enhanced Recovery Protocols (ERP)
This study is testing different ways to help people recover better and faster after having planned abdominal surgery at UPMC.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Enrollment | 2500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Pittsburgh Academic / other |
| Locations | 3 sites (Pittsburgh, Pennsylvania and 2 other locations) |
| Trial ID | NCT04606264 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates various recommended strategies for enhancing recovery in patients undergoing elective abdominal surgery at UPMC. It utilizes a randomized embedded multifactorial adaptive platform (REMAP) to assess combinations of perioperative treatments, including preoperative, intraoperative, and postoperative care. The goal is to identify optimal strategies that lead to better patient outcomes, such as fewer hospital days and improved pain management. The study will analyze data from multiple UPMC facilities to refine these strategies based on patient-specific factors.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older scheduled for elective abdominal surgeries at UPMC facilities.
Not a fit: Patients undergoing emergent surgeries or those with imminent death are unlikely to benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly improve recovery times and overall patient satisfaction after elective surgeries.
How similar studies have performed: Other studies utilizing similar enhanced recovery protocols have shown promising results, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria 1. Patient is seen in preoperative appointment prior to surgery 2. ≥ 18 years of age 3. Anticipated overnight hospital stay 4. Scheduled for elective abdominal surgery that utilizes ERP PowerPlans - placed into the patient's electronic chart at least one night before surgery 5. ERP Abdominal Complex Pathway PowerPlan (used for colorectal and gastrointestinal surgery) 6. ERP Bariatric Surgery Pathway PowerPlan 7. ERP Gynecology Oncology Pathway PowerPlan 8. ERP Whipple/Pancreas Pathway PowerPlan 9. ERP Open Liver Resection Pathway PowerPlan 10. Surgery is scheduled for one of the following UPMC sites: 11. UPMC Presbyterian Hospital 12. UPMC Passavant Hospital 13. UPMC Magee-Women's Hospital Exclusion Critera 1. Death is deemed to be imminent or inevitable 2. Patient is pregnant \< 18 years of age 3. Patients undergoing emergent/urgent surgery 4. Patients that are pregnant 5. Patients that have an eligible PowerPlan ordered less than one night before surgery
Where this trial is running
Pittsburgh, Pennsylvania and 2 other locations
- UPMC Magee-Womens Hospital — Pittsburgh, Pennsylvania, United States (Recruiting)
- UPMC Presbyterian — Pittsburgh, Pennsylvania, United States (Recruiting)
- UPMC Passavant — Pittsburgh, Pennsylvania, United States (Recruiting)
Study contacts
- Study coordinator: Jennifer Holder-Murray, MD, FACS
- Email: holdermurrayjm@upmc.edu
- Phone: 877-684-7189
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.