Improving quality of life for melanoma patients using a mobile coaching system

Pilot Study of the eHealth Application 'Cancer Patients Better Life Experience'

NA · The Netherlands Cancer Institute · NCT05827289

This study is testing if a mobile coaching app and smartwatch can help melanoma patients feel less tired and improve their quality of life while they receive immunotherapy.

Quick facts

PhaseNA
Study typeInterventional
Enrollment36 (estimated)
Ages18 Years and up
SexAll
SponsorThe Netherlands Cancer Institute (other)
Drugs / interventionsimmunotherapy
Locations1 site (Amsterdam, North Holland)
Trial IDNCT05827289 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the impact of a patient-centered mobile coaching and monitoring system, known as CAPABLE, on the health-related quality of life, particularly fatigue, in melanoma patients undergoing immunotherapy. Participants will use the CAPABLE smartphone application and a multi-sensorial smartwatch for a period of three to six months. Their experiences and fatigue levels will be assessed through questionnaires at baseline, three months, and six months, and results will be compared to a historical cohort receiving standard care. The goal is to determine if the CAPABLE system can significantly reduce fatigue compared to usual treatment.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old with histologically confirmed stage III or IV melanoma receiving immune checkpoint inhibitors.

Not a fit: Patients who are currently involved in another clinical trial or have been on active treatment for more than 12 months may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved management of fatigue and overall quality of life for melanoma patients undergoing immunotherapy.

How similar studies have performed: While this approach is innovative, similar studies have shown promise in using technology to enhance patient care and quality of life.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* \>18 years of age
* Sufficient understanding of the Dutch language
* Participants or their caregiver can use a smartphone (upon patient's consent)
* Histologically confirmed stage III or IV melanoma who receive treatment with immune checkpoint-inhibitors, according to the clinical guidelines.

Exclusion Criteria:

* Included in a clinical trial
* \>12 months on active treatment

Where this trial is running

Amsterdam, North Holland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Melanoma

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.