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Clinical trial No longer in our active list Interventional Ages 10 to 17

Improving quality of life for HIV positive mothers and their children

Official title: Joint Forces to Combat HIV: A Randomized Controlled Trial to Improve the Health-related Quality of Life (HRQoL) of HIV-positive Mothers and Children

Run by City University of Hong Kong · NCT06340698 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study tests if special support programs can help improve the quality of life for HIV positive mothers and their children in China.

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Quick facts

Study typeInterventional
Ages10 Years to 17 Years
SexAll
Enrollment180 (estimated)
SponsorCity University of Hong Kong
Academic / other
Locations1 site (Nanning, Guangxi)
Trial IDNCT06340698 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include HIV positive mothers and their perinatally infected children who are receiving HAART.

Probably not a fit

Patients who cannot complete assessments due to low education levels or physical constraints may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of resilience and adherence interventions in enhancing health-related quality of life (HRQoL) among HIV positive mothers and their perinatally infected children in China. The study will assess whether baseline resilience and treatment adherence correlate with HRQoL and whether the interventions can improve coping strategies, social support, and adherence behaviors. By focusing on both mothers and children, the trial seeks to understand the dyadic effects of these interventions on their overall well-being.

Why it matters

Potential benefit: If successful, this study could significantly enhance the quality of life for HIV positive mothers and their children.

How similar studies have gone: While there is limited information on similar studies, the approach of enhancing resilience and adherence in HIV populations has shown promise in other contexts.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

1. the child is HIV positive and perinatally infected, and receives HAART;
2. the biological mother of the child is HIV positive and receives HAART;
3. the mother is a primary caregiver of the child.

Exclusion Criteria:

1. cannot complete the assessment due to a low education level or physical constraints;
2. have been diagnosed with another life-threatening disease (e.g., cancer);
3. have experienced a traumatic event (e.g., a severe car accident or bereavement) in the past 12 months.

Where it's running

  • Guangxi Center for Disease Prevention and Control
    Nanning, Guangxi, China     Recruiting

Study contacts

  • Principal investigator: Xiaonan N. Yu, Dr. — City University of Hong Kong
  • Study coordinator: Xiaonan N. Yu, Dr.
  • Email: nancy.yu@cityu.edu.hk
  • Phone: 34429436

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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HIV 195City University of Hong Kong 8
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.