Improving quality of life for HIV positive mothers and their children
Joint Forces to Combat HIV: A Randomized Controlled Trial to Improve the Health-related Quality of Life (HRQoL) of HIV-positive Mothers and Children
This study tests if special support programs can help improve the quality of life for HIV positive mothers and their children in China.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 180 (estimated) |
| Ages | 10 Years to 17 Years |
| Sex | All |
| Sponsor | City University of Hong Kong Academic / other |
| Locations | 1 site (Nanning, Guangxi) |
| Trial ID | NCT06340698 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of resilience and adherence interventions in enhancing health-related quality of life (HRQoL) among HIV positive mothers and their perinatally infected children in China. The study will assess whether baseline resilience and treatment adherence correlate with HRQoL and whether the interventions can improve coping strategies, social support, and adherence behaviors. By focusing on both mothers and children, the trial seeks to understand the dyadic effects of these interventions on their overall well-being.
Who should consider this trial
Good fit: Ideal candidates include HIV positive mothers and their perinatally infected children who are receiving HAART.
Not a fit: Patients who cannot complete assessments due to low education levels or physical constraints may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly enhance the quality of life for HIV positive mothers and their children.
How similar studies have performed: While there is limited information on similar studies, the approach of enhancing resilience and adherence in HIV populations has shown promise in other contexts.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. the child is HIV positive and perinatally infected, and receives HAART; 2. the biological mother of the child is HIV positive and receives HAART; 3. the mother is a primary caregiver of the child. Exclusion Criteria: 1. cannot complete the assessment due to a low education level or physical constraints; 2. have been diagnosed with another life-threatening disease (e.g., cancer); 3. have experienced a traumatic event (e.g., a severe car accident or bereavement) in the past 12 months.
Where this trial is running
Nanning, Guangxi
- Guangxi Center for Disease Prevention and Control — Nanning, Guangxi, China (Recruiting)
Study contacts
- Principal investigator: Xiaonan N. Yu, Dr. — City University of Hong Kong
- Study coordinator: Xiaonan N. Yu, Dr.
- Email: nancy.yu@cityu.edu.hk
- Phone: 34429436
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.