Improving quality of life after atrial fibrillation catheter ablation by optimizing patient expectations

Optimizing Quality of Life by Improved Patient Expectation Following Atrial Fibrillation Catheter Ablation

Not applicable Interventional Evangelical Hospital Düsseldorf · NCT05557526

This trial will see if giving people with symptomatic atrial fibrillation guidance to set realistic expectations before catheter ablation reduces how much the condition affects their daily life during the first three months after the procedure.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorEvangelical Hospital Düsseldorf Academic / other
Locations2 sites (Düsseldorf, North Rhine-Westfalia and 1 other locations)
Trial IDNCT05557526 on ClinicalTrials.gov

What this trial studies

Adults with symptomatic atrial fibrillation who are scheduled for pulmonary vein isolation (catheter ablation) will be enrolled and assigned to an expectation-optimization intervention or to a control group. The intervention provides structured information and counseling designed to set realistic expectations about recovery and symptoms during the first three months after ablation (the blanking period). Participants will be followed for three months after the procedure to measure disease-related impairment and quality of life. Key eligibility includes German language fluency, non-permanent AF, and absence of psychiatric or other medical conditions that would overshadow cardiac quality-of-life measures; recruitment occurs at centers in Düsseldorf and Essen.

Who should consider this trial

Good fit: Ideal candidates are adults with symptomatic, non-permanent atrial fibrillation who are scheduled for pulmonary vein isolation, can participate in German-language counseling, and do not have major psychiatric or non-cardiac conditions that dominate quality of life.

Not a fit: Patients with permanent atrial fibrillation, AF caused by intoxication/medication/infection, significant psychiatric illness, or other medical conditions that more strongly impact quality of life may not receive benefit.

Why it matters

Potential benefit: If successful, the approach could reduce disease-related impairment and improve early post-ablation quality of life without altering the ablation itself.

How similar studies have performed: Expectation-optimization interventions have improved recovery and patient-reported outcomes in other surgical and medical settings, but targeted testing for atrial fibrillation ablation is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* symptomatic atrial fibrillation
* indication for pulmonary vein isolation
* sufficient command of the German language

Exclusion Criteria:

* age \<18 years
* permanent atrial fibrillation
* presence of psychiatric disorders which impair the study participitatin
* presence of another medical condiction which influences quality of life stronger than the cardiac condition
* atrial fibrillation induced by intoxication, medicamentation or infection
* inability to grap the course of the study

Where this trial is running

Düsseldorf, North Rhine-Westfalia and 1 other locations

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Atrial Fibrillation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.