Improving PSA-test use in general practice

Development and Evaluation of a Cluster Package Intervention to Promote an Evidence-based Use of PSA-tests in General Practice: A Cluster Randomized Trial

NA · University of Copenhagen · NCT06748456

This study is testing a new way to help doctors in Denmark use PSA tests for prostate cancer more effectively to avoid unnecessary treatments.

Quick facts

PhaseNA
Study typeInterventional
Enrollment50 (estimated)
SexAll
SponsorUniversity of Copenhagen (other)
Locations1 site (Copenhagen)
Trial IDNCT06748456 on ClinicalTrials.gov

What this trial studies

This trial evaluates a complex intervention designed to enhance the evidence-based use of prostate specific antigen (PSA) tests among general practitioners in Denmark. The intervention includes a cluster package that consists of meeting materials and resources aimed at promoting best practices in PSA testing. By engaging quality clusters of general practitioners, the study seeks to address the challenges of overdiagnosis and overtreatment associated with prostate cancer screening. The effectiveness of this approach will be assessed through a cluster randomized design.

Who should consider this trial

Good fit: Ideal candidates for this study are quality clusters of general practitioners willing to participate in discussions about PSA testing in 2025.

Not a fit: Patients who are not part of quality clusters or those who do not have access to general practitioners in Denmark may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could lead to more appropriate use of PSA testing, reducing unnecessary treatments and improving patient outcomes.

How similar studies have performed: Other studies have shown success in implementing evidence-based practices in general practice, suggesting that this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Quality clusters with a cluster coordinator
* Quality clusters willing to participate in a cluster meeting with PSA as a theme in 2025.

Exclusion Criteria:

* Quality clusters who already planned their cluster meetings in 2025.
* Quality clusters unwilling to await allocation before planning their cluster meetings in 2025.
* Quality clusters participating in the pilot study

Where this trial is running

Copenhagen

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Prostate Cancer, Evidence Based Medicine, Prostate Specific Antigen, PSA-test, Evidence based medicine, Quality clusters, General practice

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.