Improving PrEP Uptake Among Black Women
Implementation and Dissemination of Evidence-Based Interventions to Improve PrEP Care Continuum Outcomes Among Women in Community Health Clinics in the Southern U.S.
This study is testing different ways to help Black women get better access to a medication that can prevent HIV, to see if these methods make a difference in their uptake of the treatment.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 680 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Chicago Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Trial ID | NCT05626452 on ClinicalTrials.gov |
What this trial studies
This study aims to enhance the uptake of pre-exposure prophylaxis (PrEP) among Black cisgender women, who face high rates of HIV infection. The researchers will implement four strategies—provider training, patient education, electronic medical record optimization, and PrEP navigation—across 12 community health clinics in the Midwest and South. Using a stepped-wedge randomized trial design, the study will evaluate the effectiveness of these interventions by comparing outcomes before and after the implementation period. The RE-AIM framework will guide the evaluation of clinical and implementation outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are HIV-negative Black cisgender women aged 18 years or older.
Not a fit: Patients who are HIV-positive or younger than 18 years will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly increase PrEP use among Black women, thereby reducing their risk of HIV infection.
How similar studies have performed: Other studies have shown success with similar interventions aimed at increasing PrEP uptake, particularly among high-risk populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 years or older * HIV-negative Exclusion Criteria: * Younger than age 18 years * HIV-positive
Where this trial is running
Chicago, Illinois
- University of Chicago — Chicago, Illinois, United States (Recruiting)
Study contacts
- Principal investigator: Jessica Ridgway, MD, MS — University of Chicago
- Study coordinator: Jessica Ridgway, MD, MS
- Email: jridgway@medicine.bsd.uchigao.edu
- Phone: 773-702-9185
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.