Improving power training for adults with Parkinson's disease

The Effects of Top Set Training in Combination With Power Training in Subjects With Parkinson's Disease

Not applicable Interventional University of Miami · NCT06801704

This study is testing if a new way of strength training can help adults with Parkinson's disease feel stronger and more independent compared to regular power training.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages30 Years to 90 Years
SexAll
SponsorUniversity of Miami Academic / other
Locations1 site (Coral Gables, Florida)
Trial IDNCT06801704 on ClinicalTrials.gov

What this trial studies

This project aims to enhance power in adults with Parkinson's disease by comparing traditional power training with a top set resistance training approach. The top set method involves warm-up sets that gradually increase in weight until reaching 90% of the participant's maximum strength, potentially leading to better outcomes in daily activities and cognitive functions. The study will assess whether this innovative training method is more effective than conventional power training in improving independence for individuals with Parkinson's disease.

Who should consider this trial

Good fit: Ideal candidates are adults aged 30-90 with a confirmed diagnosis of Parkinson's disease and a Hoehn and Yahr score of 3 or lower.

Not a fit: Patients with uncontrolled cardiovascular disease, other neuromuscular diseases, or significant cognitive impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly enhance the independence and quality of life for patients with Parkinson's disease.

How similar studies have performed: While this specific approach is novel, similar studies focusing on resistance training have shown promising results in improving physical function in Parkinson's disease.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Confirmed diagnosis of Parkinson's disease
* Between the ages of 30-90 years of age
* A Hoehn and Yahr score of ≤3, which will be provided by the participant's medical provider within 1 year of the study's inception.

Exclusion Criteria:

* Uncontrolled cardiovascular disease that prevents participation in a training program
* Documented HIV infection or another immunodeficiency syndrome
* Other neuromuscular diseases besides Parkinson's disease
* Current musculoskeletal injury that prevents exercise.
* Having a pacemaker
* Pregnancy
* Incarcerated individuals
* Montreal Cognitive Assessment Score below 18

Where this trial is running

Coral Gables, Florida

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Parkinson Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.