Improving physical and mental health before colorectal cancer surgery
Optimization of Patients' Physical and Mental Status Prior to Colorectal Cancer Surgery -a Randomized Clinical Trial
This study is testing whether personalized support like exercise and nutrition can help people getting ready for colorectal cancer surgery recover better and face fewer complications.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 518 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Karolinska Institutet Academic / other |
| Locations | 1 site (Stockholm) |
| Trial ID | NCT04909567 on ClinicalTrials.gov |
What this trial studies
This study aims to optimize the physical and mental status of patients awaiting colorectal cancer surgery to reduce postoperative complications and enhance recovery. Patients will be randomized into an intervention group, receiving tailored support including exercise, nutritional guidance, and psychosocial support, or a control group with no interventions. The optimization center at Danderyd Hospital will provide a structured approach to patient care, involving a multidisciplinary team. Outcomes will be assessed through various clinical tests before and after the intervention.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with a strong suspicion of colorectal cancer.
Not a fit: Patients with severe cognitive impairment or dementia may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to fewer complications and faster recovery for colorectal cancer surgery patients.
How similar studies have performed: While the specific structured optimization approach has not been studied before, similar interventions in other surgical contexts have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients, 18 years or older, with strong suspicion of colorectal cancer Exclusion Criteria: * Patients with dementia with severe cognitive impairment
Where this trial is running
Stockholm
- Ulf Oskar Gustafsson — Stockholm, Sweden (Recruiting)
Study contacts
- Principal investigator: Ulf Gustafsson, MD, PhD — Karolinska Institutet
- Study coordinator: Klas Pekkari, MD, PhD,
- Email: klas.pekkari@sll.se
- Phone: 46707799817
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.