Improving physical and mental ability to keep older adults independent in Singapore
Official title: Optimizing INtrinsic Capacity for Functional INdependence and to Impede FrailTY in Older Adults: Adaptation of the WHO-ICOPE for Healthy Ageing in Singapore
Run by Sengkang General Hospital · NCT07477561 · Data updated 2026-11-12
This program will test whether regular combined screening and targeted care using apps and clinical referrals helps Singaporean adults aged 60+ stay independent and slow frailty.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 60 Years and up |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | Sengkang General Hospital Academic / other |
| Locations | 1 site (Singapore) |
| Status | Recruiting |
| Started | July 17, 2023 |
| Main results expected | June 30, 2027 |
| Study ends | January 15, 2028 |
| Registry record updated | April 17, 2026 |
| Trial ID | NCT07477561 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Community-dwelling Singapore citizens or permanent residents aged 60 or older who can provide informed consent and are able to participate in app-based and clinic-based components are ideal candidates.
✕Probably not a fit
Residents of sheltered or nursing homes, non-Singaporeans, those under 60, or people unable to consent or engage with remote tools are unlikely to benefit from this community-focused program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The program combines routine screening for frailty and intrinsic capacity with a tiered care pathway that offers technology-assisted self-screening, remote monitoring, behavioural nudges, and clinical referrals for those with identified needs. It uses tools such as the SCREENii algorithm for objective frailty assessment and the ENGAGE app for ongoing self-monitoring and engagement. Participants are randomized to immediate intervention or a wait-list control and outcomes are tracked primarily by changes in life-space mobility, with secondary measures including screening uptake, adherence to care pathways, quality of life, and implementation sustainability. The study also includes preparatory phases to establish technology readiness, care pathways, and community partnerships to support scale-up.
Why it matters
Potential benefit: If successful, the program could help older adults maintain independence, reduce functional decline, and improve quality of life through earlier detection and timely support.
How similar studies have gone: Previous multicomponent frailty and WHO-ICOPE–based programs have shown promising but mixed results, and technology-enabled community delivery represents a relatively new and less-tested approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: (in Phases 1, 2 and 3): * Any Singaporean or Permanent Resident (PR) aged 60 years and above * Able to provide informed consent (or legally acceptable representative available) Exclusion Criteria (in Phases 1, 2 and 3): * Non-Singaporeans or non-PRs under 60 years of age * Residents of sheltered or nursing homes
Where it's running
-
Sengkang General Hospital
Singapore, Singapore Recruiting
Study contacts
- Principal investigator: Laura Bee Gek Tay — Sengkang General Hospital
- Study coordinator: Denise Qian Ling Chua
- Email: infinity.icope@singhealth.com.sg
- Phone: 6580927146
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Personalized multidomain care pathway for older adults with Intrinsic Capacity decline
This study tests a personalized, ICOPE-based multidomain care plan for community-dwelling adults aged 65 and older to see if a 6-month program can be completed and sustained.
-
Alive Project: Does group exercise improve social life and health in 75+ women living alone?
This study tests whether supervised group exercise at fitness clubs helps 75-year-old and older women who live alone feel less lonely and healthier compared to exercising alone or doing usual activities.
-
Effects of a Community-based Multicomponent Exercise Program on Frailty and Sarcopenia in Older Adults
This project tests whether a real-world, community-based exercise program helps older adults stay stronger and less frail.
-
SHARP: Personalized Health and Behavior Plan to Lower Biological Age in Older Adults
A 12-month randomized trial tests whether a personalized health and behavior program can lower biological age and improve function in healthy adults over 50.
-
SPICE: Community-based pathway to screen and prevent declines in older adults' physical and mental abilities in Singapore
This program tries a digital, community screening and targeted support pathway to prevent declines in physical and mental abilities for adults aged 60 and older in Singapore.
-
L‑serine supplements with or without strength training for older adults
This trial tries daily L‑serine supplements, alone or combined with supervised strength training, to see if they improve thinking, brain health, and physical fitness in healthy 65–85‑year‑olds.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.