Improving perioperative care for heart failure patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates a multidisciplinary approach to optimize perioperative care for high-risk patients aged 65 and older undergoing non-cardiac surgery. It focuses on patients with elevated NT-proBNP levels, randomizing them into standard care or an intervention group that receives enhanced risk screening and multidimensional care. The goal is to reduce postoperative complications and improve outcomes for these patients, who are at a higher risk of cardiac issues during surgery. The study addresses the lack of systematic risk assessment structures in current clinical practice.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 65 years
* Elective non-cardiac surgical operation with intermediate or high operative risk under general anesthesia or combined anesthesia (general and regional anesthesia) as per Figure 1
* ASA (American Society of Anesthesiologists) grade ≥ II
* Qualification for randomization: NT-proBNP ≥ 450pg/ml during routine preoperative evaluation and anesthesia consultation.

Exclusion Criteria:

* Age \< 65 years
* Cardiac surgery and cardiology interventional procedures
* Transplantation surgery (e.g., kidney, liver, lung transplantation)
* Kidney surgery (e.g., nephrectomy, partial nephrectomy)
* Procedures involving cardiopulmonary bypass
* Emergency surgery
* Surgery under general anesthesia within the last 30 days
* Primary use of local or regional anesthesia
* Chronic kidney insufficiency with eGFR \< 15 ml/min or dialysis-dependent kidney insufficiency
* Surgical time \< 30 minutes
* Participation in another interventional study
* Lack of consent
* Limited language proficiency
* Patient's limited or absent capacity to provide consent, as well as patients under legal guardianship

Where it's running

• Justus Liebig University Giessen, University Hospital Giessen and Marburg
  Giessen, Germany Recruiting

Study contacts

• Study coordinator: Götz Schmidt, MD
• Email: goetz.f.schmidt@chiru.med.uni-giessen.de
• Phone: +4964198544401

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.