Improving periodontal health after third molar extraction
Using Xenograft Combined With Barrier Membrane to Improve the Formation of Deep Periodontal Pockets in the Distal of the Mandibular Second Molar After the Extraction of the Third Molar
NA · The Dental Hospital of Zhejiang University School of Medicine · NCT06318247
This study is testing if using a special bone material and a protective layer after removing wisdom teeth can help improve gum health and prevent problems for nearby teeth.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 26 Years to 45 Years |
| Sex | All |
| Sponsor | The Dental Hospital of Zhejiang University School of Medicine (other) |
| Locations | 1 site (Hangzhou, Zhejiang) |
| Trial ID | NCT06318247 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of using a xenograft combined with a barrier membrane to prevent the formation of deep periodontal pockets following the extraction of impacted mandibular third molars. The approach aims to enhance site preservation and promote better periodontal health for adjacent second molars. By utilizing organic bone xenograft material and guided bone regeneration techniques, the study seeks to address complications arising from impacted teeth and improve overall oral health outcomes. Participants will be monitored for changes in periodontal pocket depth over a six-month period post-surgery.
Who should consider this trial
Good fit: Ideal candidates are adults aged 26-45 with completely or partially impacted mandibular third molars in good oral health.
Not a fit: Patients with systemic health issues, uncontrolled periodontal conditions, or those who smoke heavily may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the risk of periodontal disease in patients with impacted third molars.
How similar studies have performed: Previous studies have shown promising results with similar approaches in periodontal therapy, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 26-45 years old * Completely or partially impacted mandibular third molar * No evidence of acute inflammation * In good physical status and oral health * Regular attendance at control visits Exclusion Criteria: * pregnancy or lactation * Aggregate systemic pathologies such as diabetes, thyroid disorders, bone metabolism diseases, among others * Patients taking calcium, bisphosphonates, glucocorticoids, or other drugs that can interfere with bone metabolism * Patients with uncontrolled periodontal conditions, endodontic conditions and other oral disorders * Heavy smoke (10 cigarettes/day or more) * The second molar has no contact with the third molar, or the third molar crown has alveolar bone
Where this trial is running
Hangzhou, Zhejiang
- Stomatology Hospital, Zhejiang University School of Medicine — Hangzhou, Zhejiang, China (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Periodontal Pocket, Periodontal Bone Loss, Impacted Third Molar Tooth