Clinical trial No longer in our active list Interventional Ages 26 to 45

Improving periodontal health after third molar extraction

Official title: Using Xenograft Combined With Barrier Membrane to Improve the Formation of Deep Periodontal Pockets in the Distal of the Mandibular Second Molar After the Extraction of the Third Molar

Run by The Dental Hospital of Zhejiang University School of Medicine · NCT06318247 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing if using a special bone material and a protective layer after removing wisdom teeth can help improve gum health and prevent problems for nearby teeth.

Quick facts

Study typeInterventional
Ages26 Years to 45 Years
SexAll
Enrollment30 (estimated)
SponsorThe Dental Hospital of Zhejiang University School of Medicine
Academic / other
Locations1 site (Hangzhou, Zhejiang)
Trial IDNCT06318247 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 26-45 with completely or partially impacted mandibular third molars in good oral health.

Probably not a fit

Patients with systemic health issues, uncontrolled periodontal conditions, or those who smoke heavily may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of using a xenograft combined with a barrier membrane to prevent the formation of deep periodontal pockets following the extraction of impacted mandibular third molars. The approach aims to enhance site preservation and promote better periodontal health for adjacent second molars. By utilizing organic bone xenograft material and guided bone regeneration techniques, the study seeks to address complications arising from impacted teeth and improve overall oral health outcomes. Participants will be monitored for changes in periodontal pocket depth over a six-month period post-surgery.

Why it matters

Potential benefit: If successful, this approach could significantly reduce the risk of periodontal disease in patients with impacted third molars.

How similar studies have gone: Previous studies have shown promising results with similar approaches in periodontal therapy, indicating potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 26-45 years old
* Completely or partially impacted mandibular third molar
* No evidence of acute inflammation
* In good physical status and oral health
* Regular attendance at control visits

Exclusion Criteria:

* pregnancy or lactation
* Aggregate systemic pathologies such as diabetes, thyroid disorders, bone metabolism diseases, among others
* Patients taking calcium, bisphosphonates, glucocorticoids, or other drugs that can interfere with bone metabolism
* Patients with uncontrolled periodontal conditions, endodontic conditions and other oral disorders
* Heavy smoke (10 cigarettes/day or more)
* The second molar has no contact with the third molar, or the third molar crown has alveolar bone

Where it's running

  • Stomatology Hospital, Zhejiang University School of Medicine
    Hangzhou, Zhejiang, China
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.