Improving outcomes for respiratory patients with low oxygen levels during exercise
Improving Post-hospitalization Outcomes of Respiratory Patients With Exertional Hypoxemia by Early Pulmonary Rehabilitation Using High Flow Nasal Oxygen- a Pilot Randomized Controlled Trial.
NA · Changi General Hospital · NCT05752370
This study is testing whether giving extra oxygen during rehab helps people with lung problems feel better when they exercise.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 56 (estimated) |
| Ages | 21 Years to 100 Years |
| Sex | All |
| Sponsor | Changi General Hospital (other) |
| Locations | 1 site (Singapore) |
| Trial ID | NCT05752370 on ClinicalTrials.gov |
What this trial studies
This pilot randomized controlled trial aims to assess the feasibility of a pulmonary rehabilitation intervention for patients experiencing exertional hypoxemia. Participants will receive high flow oxygen in addition to usual care during their rehabilitation. The study focuses on individuals diagnosed with acute COPD exacerbation, Covid-19 pneumonia, bronchiectasis, or interstitial lung disease. The primary goal is to evaluate how well this intervention can be implemented in a clinical setting.
Who should consider this trial
Good fit: Ideal candidates are adults aged 21 and above with exertional hypoxemia and specific respiratory diagnoses.
Not a fit: Patients with uncontrolled severe medical conditions or those currently enrolled in another pulmonary rehabilitation trial may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly improve the exercise capacity and overall health outcomes for patients with respiratory conditions.
How similar studies have performed: While this approach is being tested in this pilot trial, similar interventions in pulmonary rehabilitation have shown promise in improving patient outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 21 years and above * Presence of exertional hypoxemia during 1-minute sit-to-stand test * diagnosis of acute COPD exacerbation or Covid-19 pneumonia or exacerbation of bronchiectasis or exacerbation of interstitial lung disease * physically fit to participate in exercise therapy as determined by both the patient's physician and physiotherapist Exclusion Criteria: * uncontrolled severe medical conditions * currently enrolled in a pulmonary rehabilitation trial * unsuitable for randomization as determined by the patient's physician
Where this trial is running
Singapore
- Changi General Hospital — Singapore, Singapore (RECRUITING)
Study contacts
- Principal investigator: Yingjuan Mok — Changi General Hospital
- Study coordinator: Yingjuan Mok, MBBS
- Email: mok.yingjuan@singhealth.com.sg
- Phone: 69366603
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pulmonary Rehabilitation