Improving outcomes for heart failure and acute myocardial infarction patients through care coordination

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on patients hospitalized with acute decompensated heart failure (ADHF) or acute myocardial infarction (MI) to assess the effectiveness of a digital biomarker intervention called COMPASSION. The aim is to reduce hospital readmissions and improve patient outcomes by implementing evidence-based therapies and coordinated care. The study will involve monitoring patients' symptoms and treatment responses to optimize their care and minimize the risk of readmission. Participants will be recruited from multiple locations in Phoenix, Arizona.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Men and women over 18 years of age are included. Eligible subjects must be hospitalized with a primary diagnosis of ADHF or acute MI. The diagnosis of HF is established by the presence of typical symptoms, signs, and objective evidence of pulmonary congestion, elevated BNP or N-terminal pro B-type natriuretic peptide (NT-pro BNP) or impaired cardiac function. Acute MI is diagnosed by presence of chest pain, arm pain, or dyspnea with elevated Troponin and/or EKG changes suggestive of Acute coronary syndrome requiring intervention or optimal medical therapy.

Exclusion Criteria:

1. Study informed consent will be obtained before enrollment in the study for Phase 1 and Phase 2
2. All subjects 18 years or above will be a criteria for inclusion for Phase 1
3. For Phase 2, men and women 50 years or older with positive Covid19 antigen test and one other risk factor as mentioned in the comorbid section of workflow will be enrolled in the intervention arm of the study;
4. For phase 2, subjects should be able to be randomized within 48 hours of Covid19 antigen positive status
5. Patients considered unreliable by the investigator concerning the requirements for follow-up visits

Where it's running

• Multiple Locations
  Phoenix, Arizona, United States Recruiting

Study contacts

• Principal investigator: Zaki Lababidi, MD — Gilbert Cardiology
• Study coordinator: Navin Govind
• Email: vitalbeat@aventyn.com
• Phone: 2317942328

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.