Improving organ donation from brain-dead patients in ICUs
Official title: ICU Management of Brain-Dead Donors Before Multi-Organ Procurement and Factors Associated With the Number of Organs Retrieved
Run by Société Française d'Anesthésie et de Réanimation · NCT06768515 · Data updated 2026-11-12
This study looks at how to better manage brain-dead patients in ICUs to see if it can help increase the number and quality of organs available for transplant.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Société Française d'Anesthésie et de Réanimation Academic / other |
| Locations | 2 sites (Paris and 1 other locations) |
| Status | Recruiting |
| Started | April 23, 2025 |
| Main results expected | February 15, 2026 |
| Study ends | February 15, 2026 |
| Registry record updated | May 16, 2025 |
| Trial ID | NCT06768515 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients over 18 years old who are hospitalized in the ICU and have been declared brain dead with no objection to organ donation.
✕Probably not a fit
Patients who have registered an objection to organ donation or have refused the use of their data will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on the management of brain-dead donors in intensive care units (ICUs) to optimize the number and quality of organs available for transplantation. It aims to analyze the relationship between the characteristics and management of these donors and the outcomes of organ procurement. By examining hemodynamic, respiratory, and metabolic targets during the management of brain-dead donors, the study seeks to identify best practices that could lead to an increase in successful organ transplants.
Why it matters
Potential benefit: If successful, this study could enhance the availability of organs for transplantation, potentially saving more lives.
How similar studies have gone: Previous studies have indicated that optimized management of brain-dead donors can lead to improved outcomes in organ procurement, suggesting that this approach has potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients over 18 years of age, hospitalized in the ICU * In a state of brain death * No objection to organ donation during their lifetime * Patients with social security coverage Exclusion Criteria: * Objection to the use of their data during their lifetime * Registration in the national refusal registry
Where it's running
-
Hôpital Pitié Salpêtrière AP-HP
Paris, France Recruiting -
Hôpital Saint-Louis, AP-HP
Paris, France Not yet recruiting
Study contacts
- Study coordinator: Maxime COUTROT, MD
- Email: maxime.coutrot@aphp.fr
- Phone: +33 1 42 49 93 94
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.