Improving organ donation from brain-dead patients in ICUs
ICU Management of Brain-Dead Donors Before Multi-Organ Procurement and Factors Associated With the Number of Organs Retrieved
Société Française d'Anesthésie et de Réanimation · NCT06768515
This study looks at how to better manage brain-dead patients in ICUs to see if it can help increase the number and quality of organs available for transplant.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Société Française d'Anesthésie et de Réanimation (other) |
| Locations | 2 sites (Paris and 1 other locations) |
| Trial ID | NCT06768515 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on the management of brain-dead donors in intensive care units (ICUs) to optimize the number and quality of organs available for transplantation. It aims to analyze the relationship between the characteristics and management of these donors and the outcomes of organ procurement. By examining hemodynamic, respiratory, and metabolic targets during the management of brain-dead donors, the study seeks to identify best practices that could lead to an increase in successful organ transplants.
Who should consider this trial
Good fit: Ideal candidates for this study are patients over 18 years old who are hospitalized in the ICU and have been declared brain dead with no objection to organ donation.
Not a fit: Patients who have registered an objection to organ donation or have refused the use of their data will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the availability of organs for transplantation, potentially saving more lives.
How similar studies have performed: Previous studies have indicated that optimized management of brain-dead donors can lead to improved outcomes in organ procurement, suggesting that this approach has potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients over 18 years of age, hospitalized in the ICU * In a state of brain death * No objection to organ donation during their lifetime * Patients with social security coverage Exclusion Criteria: * Objection to the use of their data during their lifetime * Registration in the national refusal registry
Where this trial is running
Paris and 1 other locations
- Hôpital Saint-Louis, AP-HP — Paris, France (NOT_YET_RECRUITING)
- Hôpital Pitié Salpêtrière AP-HP — Paris, France (RECRUITING)
Study contacts
- Study coordinator: Maxime COUTROT, MD
- Email: maxime.coutrot@aphp.fr
- Phone: +33 1 42 49 93 94
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Death, Brain