Improving MRI for diagnosing anterior ischemic optic neuropathy
Official title: Diagnostic Accuracy of Optimized Diffusion-Weighted Imaging for Detecting Anterior Ischemic Optic Neuropathy
Run by Fondation Ophtalmologique Adolphe de Rothschild · NCT04451265 · Data updated 2026-11-12
This study is testing new MRI techniques to see if they can help doctors better diagnose anterior ischemic optic neuropathy in adults who have vision problems.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 250 (estimated) |
| Sponsor | Fondation Ophtalmologique Adolphe de Rothschild Research network |
| Locations | 3 sites (Lille, Lille and 2 other locations) |
| Status | Recruiting |
| Started | October 26, 2022 |
| Main results expected | September 2027 |
| Study ends | March 2028 |
| Registry record updated | January 5, 2026 |
| Trial ID | NCT04451265 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old with suspected anterior ischemic optic neuropathy who are scheduled for a brain and visual MRI.
✕Probably not a fit
Patients who cannot undergo MRI due to contraindications or those who are pregnant or breastfeeding may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to enhance the diagnostic accuracy of diffusion-weighted imaging in detecting anterior ischemic optic neuropathy (NOIA) in patients presenting with visual disturbances. Patients over 18 years old, suspected of having NOIA, will undergo a brain and visual MRI, which will include two additional sequences specifically designed for this research. The study will assess the effectiveness of these optimized imaging techniques in improving diagnosis and patient outcomes. Participation requires informed consent and affiliation with a Social Security scheme.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and timely diagnoses of anterior ischemic optic neuropathy, potentially improving patient management and outcomes.
How similar studies have gone: While there is ongoing research in imaging techniques for neuro-ophthalmological conditions, this specific approach to optimizing diffusion-weighted imaging for NOIA is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient over 18 years old * Patient with suspected NOIA, evoked after clinical examination by a specialized ophthalmologist * For which a brain and visual MRI is planned * Express consent to participate in the study * Affiliate or beneficiary of a Social Security scheme Exclusion Criteria: * Contraindication to MRI (electrical device, metallic foreign body, claustrophobia) * Patient benefiting from a legal protection measure * Pregnant or breastfeeding woman
Where it's running
-
Fondation A De Rothschild
Paris, Paris, France Recruiting -
CHU de LILLE
Lille, Lille, France Not yet recruiting -
Chu Rouen
Rouen, France Not yet recruiting
Study contacts
- Study coordinator: Amelie YAVCHITZ
- Email: ayavchitz@for.paris
- Phone: 0148036431
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.