Improving MRI for diagnosing anterior ischemic optic neuropathy
Diagnostic Accuracy of Optimized Diffusion-Weighted Imaging for Detecting Anterior Ischemic Optic Neuropathy
This study is testing new MRI techniques to see if they can help doctors better diagnose anterior ischemic optic neuropathy in adults who have vision problems.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Fondation Ophtalmologique Adolphe de Rothschild Research network |
| Locations | 3 sites (Lille, Lille and 2 other locations) |
| Trial ID | NCT04451265 on ClinicalTrials.gov |
What this trial studies
This observational study aims to enhance the diagnostic accuracy of diffusion-weighted imaging in detecting anterior ischemic optic neuropathy (NOIA) in patients presenting with visual disturbances. Patients over 18 years old, suspected of having NOIA, will undergo a brain and visual MRI, which will include two additional sequences specifically designed for this research. The study will assess the effectiveness of these optimized imaging techniques in improving diagnosis and patient outcomes. Participation requires informed consent and affiliation with a Social Security scheme.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old with suspected anterior ischemic optic neuropathy who are scheduled for a brain and visual MRI.
Not a fit: Patients who cannot undergo MRI due to contraindications or those who are pregnant or breastfeeding may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and timely diagnoses of anterior ischemic optic neuropathy, potentially improving patient management and outcomes.
How similar studies have performed: While there is ongoing research in imaging techniques for neuro-ophthalmological conditions, this specific approach to optimizing diffusion-weighted imaging for NOIA is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient over 18 years old * Patient with suspected NOIA, evoked after clinical examination by a specialized ophthalmologist * For which a brain and visual MRI is planned * Express consent to participate in the study * Affiliate or beneficiary of a Social Security scheme Exclusion Criteria: * Contraindication to MRI (electrical device, metallic foreign body, claustrophobia) * Patient benefiting from a legal protection measure * Pregnant or breastfeeding woman
Where this trial is running
Lille, Lille and 2 other locations
- CHU de LILLE — Lille, Lille, France (Not_yet_recruiting)
- Fondation A De Rothschild — Paris, Paris, France (Recruiting)
- Chu Rouen — Rouen, France (Not_yet_recruiting)
Study contacts
- Study coordinator: Amelie YAVCHITZ
- Email: ayavchitz@for.paris
- Phone: 0148036431
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.