Improving mental health in people with multiple sclerosis
Meeting an Unmet Need in Multiple Sclerosis (MS): An Evaluation of the Effectiveness of a Transdiagnostic Psychological Treatment and Its Outcomes
This study is testing if a new mental health program can help people with multiple sclerosis feel less depressed and anxious.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 24 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Kessler Foundation Academic / other |
| Locations | 1 site (East Hanover, New Jersey) |
| Trial ID | NCT05953519 on ClinicalTrials.gov |
What this trial studies
This study examines the effectiveness of the Unified Protocol in reducing depression and anxiety among individuals diagnosed with multiple sclerosis (MS). It involves a pilot randomized controlled trial (RCT) where participants will be assigned to either the intervention group receiving the Unified Protocol or a control group. The study also aims to assess secondary outcomes such as psychological well-being, quality of life (QOL), and coping strategies over time. Participants will be monitored for changes in their mental health and MS symptomatology throughout the trial.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older with a diagnosis of multiple sclerosis who are experiencing significant depression and/or anxiety.
Not a fit: Patients with other neurological illnesses, cognitive impairments, or those currently engaged in other psychological therapies may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly improve mental health and overall quality of life for patients with multiple sclerosis.
How similar studies have performed: Previous studies have shown promising results in using psychological interventions for mental health issues in chronic illness populations, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of multiple sclerosis * 18 years of age or older * Experiencing significant depression and/or anxiety * English-speaking * Able to provide informed consent * Access to the internet Exclusion Criteria: * History of any other neurological illness (e.g. traumatic brain injury, epilepsy, dementia) * Current participation in another randomized controlled trial * Cognitive impairment that would affect my ability to fully participate in the group * Unable to attend group sessions * Active participation in another formal clinical group or psychological therapy * Any other medical or psychological condition that, in the judgement of the investigators, prevents successful participation in the study
Where this trial is running
East Hanover, New Jersey
- Kessler Foundation — East Hanover, New Jersey, United States (Recruiting)
Study contacts
- Study coordinator: Belinda L Washington, BA
- Email: bwashington@kesslerfoundation.org
- Phone: 973-324-8446
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.