Improving memory and learning in older adults with mild cognitive impairment
Use of a Memory Technique to Improve New Learning and Memory in Individuals With Mild Cognitive Impairment
This study is testing if memory exercises can help older adults with mild cognitive impairment improve their learning and memory skills.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 60 Years and up |
| Sex | All |
| Sponsor | Kessler Foundation Academic / other |
| Locations | 2 sites (Ann Arbor, Michigan and 1 other locations) |
| Trial ID | NCT05396248 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of memory retraining exercises in enhancing learning and memory in individuals aged 60 and older diagnosed with Mild Cognitive Impairment (MCI). It employs a double-blind, placebo-controlled design to compare the effects of the memory retraining intervention against a placebo control. The study aims to replicate previous findings that suggest memory retraining can lead to significant improvements in cognitive performance and everyday functioning for those with MCI. By focusing on cognitive deficits that impact daily life, the trial seeks to provide a structured approach to rehabilitation for affected individuals.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 60 or older who are fluent in English and have a research-based diagnosis of Amnestic Mild Cognitive Impairment.
Not a fit: Patients with a history of significant psychiatric illness, prior neurological injury, or substance abuse may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved memory and cognitive function in patients with Mild Cognitive Impairment, enhancing their quality of life.
How similar studies have performed: Previous studies have shown promising results in improving cognitive function through memory retraining, suggesting that this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 60 or older. * read and speak English fluently. * Research based diagnosis of Amnestic Mild Cognitive Impairment Exclusion Criteria: * prior stroke or neurological injury/disease (i.e. traumatic brain injury, Multiple Sclerosis, or Stroke). * history of significant psychiatric illness (for example, bipolar disorder, schizophrenia, or psychosis). * significant alcohol or drug abuse history (inpatient treatment). * Benzodiazepines and steroid use
Where this trial is running
Ann Arbor, Michigan and 1 other locations
- University of Michigan — Ann Arbor, Michigan, United States (Recruiting)
- Kessler Foundation Research Center — West Orange, New Jersey, United States (Recruiting)
Study contacts
- Principal investigator: Nancy Chiaravalloti — Kessler Foundation
- Study coordinator: Nancy Moore
- Email: nbmoore@kesslerfoundation.org
- Phone: 1973-324-8450
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.