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Clinical trial Recruiting at 2 sites Interventional Ages 60 and up

Improving memory and learning in older adults with mild cognitive impairment

Official title: Use of a Memory Technique to Improve New Learning and Memory in Individuals With Mild Cognitive Impairment

Run by Kessler Foundation · NCT05396248 · Data updated 2026-11-12

This study is testing if memory exercises can help older adults with mild cognitive impairment improve their learning and memory skills.

Quick facts

Study typeInterventional
Ages60 Years and up
SexAll
Enrollment120 (estimated)
SponsorKessler Foundation
Academic / other
Locations2 sites (Ann Arbor, Michigan and 1 other locations)
StatusRecruiting
StartedJune 28, 2023
Main results expectedMarch 2027
Study endsMarch 2027
Registry record updatedJuly 22, 2026
Trial IDNCT05396248 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals aged 60 or older who are fluent in English and have a research-based diagnosis of Amnestic Mild Cognitive Impairment.

Probably not a fit

Patients with a history of significant psychiatric illness, prior neurological injury, or substance abuse may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of memory retraining exercises in enhancing learning and memory in individuals aged 60 and older diagnosed with Mild Cognitive Impairment (MCI). It employs a double-blind, placebo-controlled design to compare the effects of the memory retraining intervention against a placebo control. The study aims to replicate previous findings that suggest memory retraining can lead to significant improvements in cognitive performance and everyday functioning for those with MCI. By focusing on cognitive deficits that impact daily life, the trial seeks to provide a structured approach to rehabilitation for affected individuals.

Why it matters

Potential benefit: If successful, this study could lead to improved memory and cognitive function in patients with Mild Cognitive Impairment, enhancing their quality of life.

How similar studies have gone: Previous studies have shown promising results in improving cognitive function through memory retraining, suggesting that this approach may be effective.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* 60 or older.
* read and speak English fluently.
* Research based diagnosis of Amnestic Mild Cognitive Impairment

Exclusion Criteria:

* prior stroke or neurological injury/disease (i.e. traumatic brain injury, Multiple Sclerosis, or Stroke).
* history of significant psychiatric illness (for example, bipolar disorder, schizophrenia, or psychosis).
* significant alcohol or drug abuse history (inpatient treatment).
* Benzodiazepines and steroid use

Where it's running

  • University of Michigan
    Ann Arbor, Michigan, United States     Recruiting
  • Kessler Foundation Research Center
    West Orange, New Jersey, United States     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Mild Cognitive Impairment 267Kessler Foundation 35
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.