Improving medication management for seniors with major neurocognitive disorders

GPS Project - Evaluation of the Impact of the Reorganization of Work Into a Family Medicine Group on Pharmacotherapy and Support for the Autonomy of Seniors With Major Neurocognitive Disorders

Not applicable Interventional CHU de Quebec-Universite Laval · NCT04889794

This study is testing a new way for doctors, nurses, and pharmacists to work together to help seniors with major neurocognitive disorders manage their medications better and stay healthy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment400 (estimated)
Ages65 Years and up
SexAll
SponsorCHU de Quebec-Universite Laval Academic / other
Locations2 sites (Montreal, Quebec and 1 other locations)
Trial IDNCT04889794 on ClinicalTrials.gov

What this trial studies

This project aims to enhance pharmacotherapy for seniors with major neurocognitive disorders by implementing a new care model that promotes collaboration among healthcare professionals, including pharmacists, nurses, and doctors. The intervention involves knowledge exchange sessions and support for seniors to reduce polypharmacy and inappropriate medications while maintaining their cognitive health and autonomy. Approximately 400 seniors will be divided into intervention and control groups to evaluate the effectiveness of the new care approach over a 12-month period, with follow-up assessments conducted for about 6 months.

Who should consider this trial

Good fit: Ideal candidates are seniors aged 65 and older who are undergoing cognitive evaluation or have been diagnosed with major neurocognitive disorders and are taking prescription medications.

Not a fit: Patients in palliative care or those unable to respond to questionnaires in French without a caregiver may not benefit from this study.

Why it matters

Potential benefit: If successful, this project could significantly improve the quality of life and cognitive health of seniors with major neurocognitive disorders.

How similar studies have performed: Other studies have shown promise in optimizing pharmacotherapy for seniors with cognitive impairments, indicating that this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All seniors (65 years of age or older) undergoing cognitive evaluation OR referred to a memory clinic OR having been diagnosed with cognitive impairment within the last year OR with MCND and followed up at home AND,
* referred to the pharmacist, for the FMGs exposed
* taking prescription medications

Exclusion Criteria:

* Seniors in palliative care OR
* unable to answer questionnaires in French AND without a caregiver.

Where this trial is running

Montreal, Quebec and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Major Neurocognitive Disorderliving labmajor neurocognitive disorderpolypharmacyhealth outcomespharmacistshome carefamily medicine groups
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.