Improving medication adherence for Latinx patients with hypertension

Bridging the Evidence-to-practice Gap: Evaluating Practice Facilitation as a Strategy to Accelerate Translation of a Systems-level Adherence Intervention Into Safety Net Practices

Phase 4 Interventional NYU Langone Health · NCT03713515

This study tests a new way to help Latinx patients with high blood pressure stick to their medication and improve their health through coaching and support.

Quick facts

PhasePhase 4
Study typeInterventional
Enrollment700 (estimated)
Ages18 Years to 90 Years
SexAll
SponsorNYU Langone Health Academic / other
Locations1 site (New York, New York)
Trial IDNCT03713515 on ClinicalTrials.gov

What this trial studies

This project evaluates the effectiveness of a quality improvement method called practice facilitation to enhance the implementation of an evidence-based intervention aimed at improving medication adherence and blood pressure control among Latinx patients with uncontrolled hypertension. The intervention involves identifying patients who are non-adherent to their antihypertensive medications and providing them with health coaching, care planning, and monitoring to improve their health outcomes. The study will assess the fidelity of the intervention implementation and measure clinical outcomes at 12 months.

Who should consider this trial

Good fit: Ideal candidates for this study are Latinx adults aged 18 and older with uncontrolled hypertension who are non-adherent to their antihypertensive medications.

Not a fit: Patients who are adherent to their antihypertensive medications or do not have uncontrolled hypertension may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve medication adherence and blood pressure control in Latinx patients with hypertension.

How similar studies have performed: Other studies have shown success in using practice facilitation to improve health outcomes, making this approach promising but still requiring further validation in this specific population.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Self-identify as Latino
* Be fluent in English or Spanish
* Be age 18 years or older
* Receiving care in a safety-net primary care practice
* Have uncontrolled HTN documented in the electronic health record (EHR) on at least two visits in the past year (defined as an average BP ≥ 140/90 mmHg)
* Have been prescribed at least one anti-hypertensive medication and be non- adherent to their medications, defined as adherence \<80% in the preceding 12 months, as determined by prescription orders obtained from the clinic EHR.

Clinic and nonclinical staff inclusion criteria:

• Primary care provider (MD/DO, NP), Nurse, Medical Assistant, or administrative staff employed at the participating practices and (b) interacts with at least five patients with a diagnosis of hypertension.

Exclusion Criteria:

* Being deemed unable to comply with the study protocol (either self-selected or by indicating during screening that s/he could not complete all requested tasks)
* Participation in other hypertension-related clinical trials
* Have significant psychiatric comorbidity or reports of substance abuse (as documented in the EHR)
* Plan to discontinue care at their practice within the next 12 months

Clinic and nonclinical staff exclusion criteria:

• Refuse to participate

Where this trial is running

New York, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hypertension
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.