Improving long-term survival for organ transplant patients
Optimizing Long-term Survival in Organ Transplantation: From Physiopathology to Optimized Patient Management
This study is testing ways to improve the long-term success of organ transplants by personalizing care and collecting samples from patients to better predict and prevent transplant rejection.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 430 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Limoges Academic / other |
| Locations | 4 sites (Limoges and 3 other locations) |
| Trial ID | NCT03997253 on ClinicalTrials.gov |
What this trial studies
This study aims to enhance the long-term success of organ transplantation by optimizing donor and recipient management and personalizing follow-up care. It focuses on identifying factors that contribute to long-term graft and patient survival through translational research and biological sample collection. Participants will provide blood and urine samples to help predict transplant rejection and improve patient outcomes.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 who have received a kidney, liver, or heart transplant and are being followed by one of the participating FHU SUPORT centers.
Not a fit: Patients who are unable to understand the information provided or are under legal protection may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly improve the long-term survival rates and quality of life for organ transplant recipients.
How similar studies have performed: Other studies have shown promise in optimizing organ transplant outcomes through personalized management strategies, making this approach both relevant and potentially impactful.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or female over 18 (no age limit) * affiliated to a social security organization * Recipient (s) of a kidney, liver or heart transplant * followed by at least one of the FHU SUPORT centers (Tours, Poitiers, Limoges, Rennes) * having given informed consent to participate in the cohort. Exclusion Criteria: * Patient unable to understand the information given by the investigator * People under the protection of justice
Where this trial is running
Limoges and 3 other locations
- Limoges hospital — Limoges, France (Recruiting)
- Poitiers Hospital — Poitiers, France (Recruiting)
- Rennes Hospital — Rennes, France (Not_yet_recruiting)
- Tours hospital — Tours, France (Recruiting)
Study contacts
- Study coordinator: Sophie ALAIN, MD
- Email: sophie.alain@unilim.fr
- Phone: +33 5 55 056 728
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.