Improving long-term survival for organ transplant patients
Official title: Optimizing Long-term Survival in Organ Transplantation: From Physiopathology to Optimized Patient Management
Run by University Hospital, Limoges · NCT03997253 · Data updated 2026-11-12
This study is testing ways to improve the long-term success of organ transplants by personalizing care and collecting samples from patients to better predict and prevent transplant rejection.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 430 (estimated) |
| Sponsor | University Hospital, Limoges Academic / other |
| Locations | 4 sites (Limoges and 3 other locations) |
| Status | Recruiting |
| Started | December 21, 2020 |
| Main results expected | June 2027 |
| Study ends | June 2027 |
| Registry record updated | June 29, 2026 |
| Trial ID | NCT03997253 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults over 18 who have received a kidney, liver, or heart transplant and are being followed by one of the participating FHU SUPORT centers.
✕Probably not a fit
Patients who are unable to understand the information provided or are under legal protection may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to enhance the long-term success of organ transplantation by optimizing donor and recipient management and personalizing follow-up care. It focuses on identifying factors that contribute to long-term graft and patient survival through translational research and biological sample collection. Participants will provide blood and urine samples to help predict transplant rejection and improve patient outcomes.
Why it matters
Potential benefit: If successful, this study could significantly improve the long-term survival rates and quality of life for organ transplant recipients.
How similar studies have gone: Other studies have shown promise in optimizing organ transplant outcomes through personalized management strategies, making this approach both relevant and potentially impactful.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or female over 18 (no age limit) * affiliated to a social security organization * Recipient (s) of a kidney, liver or heart transplant * followed by at least one of the FHU SUPORT centers (Tours, Poitiers, Limoges, Rennes) * having given informed consent to participate in the cohort. Exclusion Criteria: * Patient unable to understand the information given by the investigator * People under the protection of justice
Where it's running
-
Limoges hospital
Limoges, France Recruiting -
Poitiers Hospital
Poitiers, France Recruiting -
Tours hospital
Tours, France Recruiting -
Rennes Hospital
Rennes, France Not yet recruiting
Study contacts
- Study coordinator: Sophie ALAIN, MD
- Email: sophie.alain@unilim.fr
- Phone: +33 5 55 056 728
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Education and a smartphone app to help organ transplant patients manage life, meds, and symptoms
A smartphone app plus teaching materials are tested to see if they improve quality of life and adherence to immunosuppressive therapy for adults who have had a liver or kidney transplant.
-
Survey on medication information leaflets for organ transplant patients
This study is trying to find out what organ transplant patients and their caregivers think about the medication information leaflets to make them clearer and more helpful.
-
Collection of biological materials from organ transplant patients
This study is collecting samples from organ transplant patients to help researchers learn more about why transplants sometimes fail and to find better ways to detect rejection and other related issues.
-
Developing a library of samples from organ transplant patients
This study is collecting blood, tissue, and urine samples from organ transplant patients and healthy volunteers to see how their bodies respond to transplant treatments and medications.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.