Improving lifestyle and sleep for inactive adults

Effects of a Lifestyle and Sleep Intervention Program on Quality of Life and Physical Activity Levels in Non-exercising Adults, SPIRAL+ Randomized Controlled Trial

Not applicable Interventional University Hospital, Grenoble · NCT06424847

This study is testing a program that combines exercise, better eating, and sleep improvement to see if it helps inactive adults become healthier and lower their risk of heart disease.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment201 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorUniversity Hospital, Grenoble Academic / other
Locations1 site (Grenoble)
Trial IDNCT06424847 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effects of a comprehensive lifestyle intervention that includes physical activity, diet, and sleep improvement strategies in adults who are physically inactive. Participants will be engaged in a program designed to enhance their overall health and reduce the risk of cardiovascular diseases through behavior modification techniques. The study will compare the outcomes of those receiving the lifestyle and sleep intervention against a health education intervention. By addressing both lifestyle and sleep, the study seeks to fill a gap in current prevention strategies for cardiovascular health.

Who should consider this trial

Good fit: Ideal candidates are physically inactive adults aged 18 to 80 who can participate in regular physical activity and provide informed consent.

Not a fit: Patients with diagnosed sleep disturbances or those who are currently participating in another interventional study may not benefit from this intervention.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce the risk of cardiovascular diseases in inactive adults by promoting healthier lifestyles and better sleep.

How similar studies have performed: Other studies have shown promising results with lifestyle interventions, but the specific combination of lifestyle and sleep interventions in this context is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participant who is physically inactive (i.e. less than 150 minutes of moderate intensity physical activity per week)
* Participant aged 18 to 80 years old
* Participant able to provide written informed consent
* Participant able to participate in regular physical activity (no medical contraindication to exercise)
* Participant affiliated to social security or a similar regimen

Exclusion Criteria:

* Any condition that in the opinion of the responsible physician or investigator makes the potential participant unsuitable for the study
* A participant who scores 11111 on the EQ-5D-5L questionnaire
* A diagnosed and treated sleep disturbance (sleep apnea, insomnia, restless legs syndrome)
* Persons concerned by articles L1121-5, L1121-6 and L1121-8 of the public health code (i.e. pregnancy, person deprived of liberty or subject to a legal protection measure, vulnerable person or legally protected adult)
* Person already included in another interventional study

Where this trial is running

Grenoble

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Inactivity, PhysicalLifestyle Risk Reductionlifestyle interventionsleep interventionphysical activitybehavior change techniques
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.