Improving hypertension care for people living with HIV in Uganda
PULESA Uganda: Strengthening the Blood Pressure Care and Treatment Cascade for Ugandans Living With HIV-ImpLEmentation Strategies to SAve Lives
This study is testing two different ways to improve high blood pressure care for people living with HIV in Uganda to see which one works better and is easier to use.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 48000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Infectious Diseases Research Collaboration, Uganda Academic / other |
| Locations | 16 sites (Kampala and 15 other locations) |
| Trial ID | NCT05609513 on ClinicalTrials.gov |
What this trial studies
This study aims to enhance the management of hypertension among individuals living with HIV in Uganda by comparing two strategies: a lower-resource intensive approach and a higher resource intensive approach. It will assess the effectiveness, scalability, and cost-effectiveness of integrating hypertension care into existing HIV clinics. The study will first explore current practices and barriers to hypertension management, followed by the development of a tailored implementation strategy using a human-centered design approach. The goal is to improve blood pressure treatment adherence and outcomes in urban and peri-urban settings.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years of age who are receiving care at participating HIV clinics in Uganda.
Not a fit: Patients under 18 years of age or those not diagnosed with HIV will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly improve hypertension management for people living with HIV, leading to better overall health outcomes.
How similar studies have performed: Other studies have shown success in integrating chronic disease management into HIV care, making this approach promising yet contextually adapted for Uganda.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1) All patients over 18 years of age receiving care at participating HIV clinics will contribute data for the effectiveness outcomes Exclusion Criteria: 1) Patients who are not diagnosed with HIV receiving care at participating HIV clinics and are under the age of 18.
Where this trial is running
Kampala and 15 other locations
- Butabika — Kampala, Uganda (Recruiting)
- Kawala — Kampala, Uganda (Recruiting)
- Kisenyi — Kampala, Uganda (Recruiting)
- Kitebi — Kampala, Uganda (Recruiting)
- Komamboga — Kampala, Uganda (Recruiting)
- Mengo Hospital — Kampala, Uganda (Recruiting)
- Naguru — Kampala, Uganda (Recruiting)
- Nsambya — Kampala, Uganda (Recruiting)
- Bweyogerere — Wakiso, Uganda (Recruiting)
- Entebbe RRH — Wakiso, Uganda (Recruiting)
- Kakiri — Wakiso, Uganda (Recruiting)
- Kawanda — Wakiso, Uganda (Recruiting)
- Nakawuka HCIII — Wakiso, Uganda (Recruiting)
- Nsangi HCIII — Wakiso, Uganda (Recruiting)
- Nurture Africa — Wakiso, Uganda (Recruiting)
- Saidina — Wakiso, Uganda (Recruiting)
Study contacts
- Principal investigator: Fred C. Semitala, MBChB, MMED — Infectious Diseases Research Collaboration
- Study coordinator: Fred C. Semitala, MBChB, MMED
- Email: semitala@gmail.com
- Phone: +256 (0) 772524416
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.