Improving how people tolerate upsetting feelings

Targeting Components of Distress Tolerance

Not applicable Interventional University of Arkansas, Fayetteville · NCT06570603

This project will test whether brief trainings that increase willingness to feel upset and boost confidence for withstanding distress help adults with high emotional distress use better emotion-regulation strategies in daily life.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment240 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Arkansas, Fayetteville Academic / other
Locations1 site (Fayetteville, Arkansas)
Trial IDNCT06570603 on ClinicalTrials.gov

What this trial studies

Adults with elevated depression, anxiety, or stress symptoms and higher distress intolerance use a smartphone app to report moods, willingness to feel upset, self-efficacy for withstanding distress, and emotion-regulation strategies multiple times per day for three weeks. Participants receive brief, targeted interventions focused on willingness, self-efficacy, or psychoeducation delivered through the app and related materials. The trial examines whether these trainings change momentary emotion-regulation strategy use and whether such changes are linked to reductions in mental health symptoms over time. Baseline and follow-up questionnaires supplement the daily phone-based measurements to track symptom change.

Who should consider this trial

Good fit: Adults fluent in English who own an Android or iPhone, can regularly access their phone and internet, and have elevated symptom scores (DASS-21 ≥ 42) and Distress Intolerance Index ≥ 3 are ideal candidates.

Not a fit: People without a smartphone or reliable internet, those whose work or school prevents consistent phone access, and individuals with low symptom or distress-intolerance scores are unlikely to benefit from this intervention.

Why it matters

Potential benefit: If successful, this approach could help people manage upsetting emotions more effectively and reduce symptoms of anxiety and depression by improving moment-to-moment emotion regulation.

How similar studies have performed: Acceptance-based and self-efficacy interventions (for example, ACT and DBT skills training) have shown promise for improving distress tolerance and emotion regulation, but delivering brief targeted trainings via smartphone with intensive daily measurement is a relatively new approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Fluent in English
* Uses Android or iPhone smartphone
* Depression Anxiety and Stress Scale (DASS-21) scores of 42 and higher
* Distress Intolerance Index (DII) scores of 3 or higher

Exclusion Criteria:

* Work or School that does not allow consistent access to phone (or is unsafe)
* No internet access for completing follow-up surveys

Where this trial is running

Fayetteville, Arkansas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Distress, Emotional
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.