Improving HIV care and treatment adherence among adolescents through social networks

Understanding and Developing a Network-based Social Support Intervention to Improve Retention in Human Immunodeficiency Virus (HIV) Care and Antiretroviral Therapy Adherence for Adolescents Living With HIV

Not applicable Interventional Wake Forest University Health Sciences · NCT04077047

This study is testing a new way to help teenagers with HIV stay in care and stick to their treatment by using their friends and social connections for support.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages15 Years to 21 Years
SexAll
SponsorWake Forest University Health Sciences Academic / other
Locations2 sites (Winston-Salem, North Carolina and 1 other locations)
Trial IDNCT04077047 on ClinicalTrials.gov

What this trial studies

This study aims to enhance the retention and adherence of adolescents living with HIV (ALWH) in care by leveraging their social networks. It involves a preparatory phase where researchers will gather data from various sources to develop a theoretical model that informs the intervention. The study will utilize social network analyses to understand how these networks impact ALWH's engagement with HIV care and treatment. Following this, participatory methods will be employed to create a tailored social support intervention, which will be piloted to assess its acceptability, feasibility, safety, and efficacy.

Who should consider this trial

Good fit: Ideal candidates for this study are adolescents aged 15-24 living with HIV who reside in the study area and can engage their social network in the intervention.

Not a fit: Patients who are not living with HIV or those who cannot recruit a social network member for participation may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve treatment adherence and retention in care for adolescents living with HIV, ultimately reducing morbidity and mortality.

How similar studies have performed: Other studies have shown promise in using social networks to improve health outcomes, suggesting that this approach could be effective, though this specific intervention is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* reside in study area
* able to provide consent or assent
* agreeable to allowing the research team to have access to their clinic data to assess retention in human immunodeficiency virus- (HIV) care and antiretroviral therapy (ART) adherence
* each Adolescents living with HIV (ALWH) must recruit at least one social network member to participate in the intervention with them

Exclusion Criteria:

* None

Where this trial is running

Winston-Salem, North Carolina and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HIV/AIDSAdolescents
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.