Improving HIV care and treatment adherence among adolescents through social networks
Official title: Understanding and Developing a Network-based Social Support Intervention to Improve Retention in Human Immunodeficiency Virus (HIV) Care and Antiretroviral Therapy Adherence for Adolescents Living With HIV
Run by Wake Forest University Health Sciences · NCT04077047 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing a new way to help teenagers with HIV stay in care and stick to their treatment by using their friends and social connections for support.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 15 Years to 21 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Wake Forest University Health Sciences Academic / other |
| Locations | 2 sites (Winston-Salem, North Carolina and 1 other locations) |
| Trial ID | NCT04077047 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adolescents aged 15-24 living with HIV who reside in the study area and can engage their social network in the intervention.
✕Probably not a fit
Patients who are not living with HIV or those who cannot recruit a social network member for participation may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to enhance the retention and adherence of adolescents living with HIV (ALWH) in care by leveraging their social networks. It involves a preparatory phase where researchers will gather data from various sources to develop a theoretical model that informs the intervention. The study will utilize social network analyses to understand how these networks impact ALWH's engagement with HIV care and treatment. Following this, participatory methods will be employed to create a tailored social support intervention, which will be piloted to assess its acceptability, feasibility, safety, and efficacy.
Why it matters
Potential benefit: If successful, this intervention could significantly improve treatment adherence and retention in care for adolescents living with HIV, ultimately reducing morbidity and mortality.
How similar studies have gone: Other studies have shown promise in using social networks to improve health outcomes, suggesting that this approach could be effective, though this specific intervention is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * reside in study area * able to provide consent or assent * agreeable to allowing the research team to have access to their clinic data to assess retention in human immunodeficiency virus- (HIV) care and antiretroviral therapy (ART) adherence * each Adolescents living with HIV (ALWH) must recruit at least one social network member to participate in the intervention with them Exclusion Criteria: * None
Where it's running
-
Wake Forest University School of Medicine
Winston-Salem, North Carolina, United States Recruiting -
Desmond Tutu Health Foundation
Cape Town, South Africa Recruiting
Study contacts
- Principal investigator: Tiarney Ritchwood, PhD — Wake Forest University Health Sciences
- Study coordinator: Tiarney Ritchwood, PhD
- Email: tritchwo@wakehealth.edu
- Phone: 336-713-4238
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Peer-led Dynamic Choice HIV Prevention for Women
This trial tests a peer-led HIV prevention approach to see if it helps women at higher risk in Uganda better prevent HIV than standard care.
-
Improving long-term medication adherence for HIV treatment
This study is testing whether daily text messages and rewards can help people starting HIV treatment stick to their medication plan over the long term.
-
Using a mobile app to reduce HIV infections in young men and non-binary individuals
This study is testing a mobile app designed to help young men and non-binary individuals reduce their risk of getting HIV.
-
Mobile intervention for HIV prevention in young men who have sex with men
This study is testing a mobile program that helps young men who have sex with men learn about and access HIV prevention methods, like PrEP, to see if it can reduce their risk of getting HIV.
-
A program to improve PrEP use among young women in Kenya
This study is testing a new program to help young women in Kenya use HIV prevention medication more effectively by providing support and resources tailored to their needs.
-
Using a pill sensor system to improve HIV treatment adherence
This study is testing a new pill sensor system to see if it helps adults with HIV stick to their treatment better and improve their health.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.