Clinical trial No longer in our active list Interventional Ages 15 to 21

Improving HIV care and treatment adherence among adolescents through social networks

Official title: Understanding and Developing a Network-based Social Support Intervention to Improve Retention in Human Immunodeficiency Virus (HIV) Care and Antiretroviral Therapy Adherence for Adolescents Living With HIV

Run by Wake Forest University Health Sciences · NCT04077047 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing a new way to help teenagers with HIV stay in care and stick to their treatment by using their friends and social connections for support.

More HIV/AIDS trials

Quick facts

Study typeInterventional
Ages15 Years to 21 Years
SexAll
Enrollment30 (estimated)
SponsorWake Forest University Health Sciences
Academic / other
Locations2 sites (Winston-Salem, North Carolina and 1 other locations)
Trial IDNCT04077047 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adolescents aged 15-24 living with HIV who reside in the study area and can engage their social network in the intervention.

Probably not a fit

Patients who are not living with HIV or those who cannot recruit a social network member for participation may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to enhance the retention and adherence of adolescents living with HIV (ALWH) in care by leveraging their social networks. It involves a preparatory phase where researchers will gather data from various sources to develop a theoretical model that informs the intervention. The study will utilize social network analyses to understand how these networks impact ALWH's engagement with HIV care and treatment. Following this, participatory methods will be employed to create a tailored social support intervention, which will be piloted to assess its acceptability, feasibility, safety, and efficacy.

Why it matters

Potential benefit: If successful, this intervention could significantly improve treatment adherence and retention in care for adolescents living with HIV, ultimately reducing morbidity and mortality.

How similar studies have gone: Other studies have shown promise in using social networks to improve health outcomes, suggesting that this approach could be effective, though this specific intervention is novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* reside in study area
* able to provide consent or assent
* agreeable to allowing the research team to have access to their clinic data to assess retention in human immunodeficiency virus- (HIV) care and antiretroviral therapy (ART) adherence
* each Adolescents living with HIV (ALWH) must recruit at least one social network member to participate in the intervention with them

Exclusion Criteria:

* None

Where it's running

  • Wake Forest University School of Medicine
    Winston-Salem, North Carolina, United States
    Recruiting
  • Desmond Tutu Health Foundation
    Cape Town, South Africa
    Recruiting

Study contacts

  • Principal investigator: Tiarney Ritchwood, PhD — Wake Forest University Health Sciences
  • Study coordinator: Tiarney Ritchwood, PhD
  • Email: tritchwo@wakehealth.edu
  • Phone: 336-713-4238

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.