Improving hepatitis B care for foreign-born individuals in the US

Optimizing HBV Care Cascade Among Foreign-Born in the United States (FOCUS-HBV Study)

Observational National Institutes of Health Clinical Center (CC) · NCT05621304

This study is trying to understand the challenges that foreign-born adults in the US with chronic hepatitis B face in getting care, so that healthcare can be improved for them.

Quick facts

Study typeObservational
Enrollment255 (estimated)
Ages18 Years to 100 Years
SexAll
SponsorNational Institutes of Health Clinical Center (CC) NIH
Locations2 sites (Los Angeles, California and 1 other locations)
Trial IDNCT05621304 on ClinicalTrials.gov

What this trial studies

This observational study aims to identify and understand the barriers that foreign-born adults in the US face in accessing care for chronic hepatitis B virus (HBV) infections. Participants aged 18 and older, who have been diagnosed with chronic HBV and were born outside the US, will visit the NIH clinic once to complete surveys. The study will assess the impact of recent immigration on the progression through the HBV care cascade and explore factors such as acculturation and language proficiency that may affect healthcare retention. The goal is to optimize care for this population by addressing identified barriers.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who have been diagnosed with chronic HBV and were born outside of the United States.

Not a fit: Patients who do not have chronic HBV or were born in the United States will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved healthcare access and outcomes for foreign-born individuals with chronic HBV.

How similar studies have performed: While there have been studies addressing healthcare access for HBV, this specific approach focusing on foreign-born individuals and their unique barriers is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
* INCLUSION CRITERIA:

In order to be eligible to participate in this study, an individual must meet all of the following criteria:

* Male or female, aged \>=18 years
* Diagnosed of chronic HBV (HBsAg-positive)
* Self-reported country of birth outside of the US

EXCLUSION CRITERIA:

An individual who meets any of the following criteria will be excluded from participation in this study:

-Individuals not able to understand and sign the informed consent document will not be included in the study.

Where this trial is running

Los Angeles, California and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic Hepatitis B VirusHealthcare RetentionNatural HistoryAcculturation-Related Barriers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.