Improving heart failure treatment with advanced imaging techniques

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to enhance cardiac resynchronization therapy (CRT) by analyzing the activation times of the left and right ventricles using non-invasive imaging techniques. It utilizes patient-specific anatomical data obtained from cardiac magnetic resonance imaging to create a semi-automated model that incorporates the conductivity of various tissues. The study employs a software package to calculate local activation times, which will help optimize CRT device programming algorithms for better patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* patients after successful implantation of a CRT-D or CRT-P device in whom a cardiac magnetic resonance examination is possible and the device is equipped with the SyncAV® programming software
* left bundle branch block before CRT implantation
* PQ interval ≤ 250 ms before implantation

Exclusion Criteria:

* high-grade AV block
* any contraindication concerning a safe CMR performance including claustrophobia
* terminal heart failure (NYHA IV) or cardiac decompensation
* life expectancy \< 1 year
* women with child-bearing potential, pregnancy
* drug abusus

Where it's running

• Medical University Innsbruck
  Innsbruck, Tyrol, Austria Recruiting

Study contacts

• Principal investigator: Wolfgang Dichtl, MD PhD — Medical University Innsbruck
• Study coordinator: Wolfgang Dichtl, MD PhD
• Email: dichtl@me.com
• Phone: 004351250481388

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.