Improving heart failure treatment through digital nudges for cardiologists

Assessment of Digital Care on Clinical Impact and Efficiency Using a Stepped Wedge Cluster RCT in Heart Failure Patients: the ADMINISTER II Trial

Not applicable Interventional Medisch Spectrum Twente · NCT06844006

This study is testing if digital reminders can help cardiologists follow heart failure treatment guidelines better, which could lead to fewer hospital visits and improved survival for patients.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment1320 (estimated)
Ages18 Years and up
SexAll
SponsorMedisch Spectrum Twente Academic / other
Locations1 site (Enschede, Overijssel)
Trial IDNCT06844006 on ClinicalTrials.gov

What this trial studies

This study investigates how nudging cardiologists can enhance their adherence to guideline-directed medical therapy (GDMT) for heart failure patients. Utilizing a stepped wedge randomized controlled trial design, the research assesses the effectiveness of digital decision support that incorporates home monitoring and clinical data. The primary outcomes measured include rates of heart failure-related hospitalizations and all-cause mortality, aiming to improve patient outcomes through better medication management.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years diagnosed with heart failure.

Not a fit: Patients who do not understand the Dutch language or have severe psychological disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved medication adherence and better health outcomes for heart failure patients.

How similar studies have performed: Other studies have shown promise in using nudging techniques to improve clinical decision-making, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All heart failure diagnoses
* \>18 years

Exclusion Criteria:

* Not understanding the Dutch Language.
* Allergies that make uptitration impossible.
* Admission to hospice or palliative care.
* Severe psychological disorders.

Where this trial is running

Enschede, Overijssel

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Heart FailureDigitial CareHome monitoringNudging
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.