Improving hearing aids with real-time AI speech enhancement
Real-time Artificial Intelligence-based Speech Enhancement Methods for Hearing Aid Improvement
This study is testing a new AI technology to see if it can help people with Auditory Neuropathy Spectrum Disorders understand speech better in noisy places when using hearing aids.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Institut Pasteur Industry-sponsored |
| Locations | 1 site (Paris) |
| Trial ID | NCT05985473 on ClinicalTrials.gov |
What this trial studies
This study focuses on individuals with Auditory Neuropathy Spectrum Disorders (ANSD), who often do not benefit from traditional hearing aids due to their unique hearing impairments. The research aims to develop and implement artificial intelligence-based denoising methods to enhance speech intelligibility in noisy environments for these patients. Participants will undergo a series of audiological tests and follow-up visits over a period of up to three years to evaluate the effectiveness of these new methods. The study also includes normal hearing participants for comparative analysis.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who are French speakers and have specific hearing loss characteristics related to ANSD.
Not a fit: Patients with conductive or mixed hearing loss, asymmetric hearing loss, or significant ear disease will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly improve the quality of life for patients with ANSD by enhancing their ability to understand speech in noisy environments.
How similar studies have performed: While the approach of using AI for speech enhancement is gaining traction, this specific application for ANSD is relatively novel and has not been extensively tested in previous studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: For all participants: * Age greater than or equal to 18 years, * French mother tongue, * Have an average tonal hearing loss (calculated according to the BIAP method) \< 30 dB HL, on headphones, for each ear, * Be professionally active, not be pre-retired and not be unemployed * Be affiliated with a social security plan, For participants with TSNA: \- Have degraded comprehension in noise (threshold of Intelligibility in Noise \> 3 dB compared to the norm). For controls: \- Have normal comprehension in noise (Intelligibility in Noise threshold ≤ 3 dB from the norm). Exclusion Criteria: For all participants: * Have a conductive or mixed hearing loss, which is when the hearing loss affects both the outer and/or middle ear and the inner ear. * Have an asymmetric hearing loss, i.e. a difference in average hearing loss between the left and right ear greater than 30 dB, * Have sequelae of ear infections and/or a history of ENT disease that permanently affects hearing (vestibular schwannoma, Meniere's disease, sudden or fluctuating deafness, congenital hypoacusis) * Being under guardianship, * Being deprived of liberty by judicial or administrative decision, or being subject to legal protection.
Where this trial is running
Paris
- CEntre de Recherche et d'Innovation en Audiologie Humaine — Paris, France (Recruiting)
Study contacts
- Principal investigator: Paul Avan, MD — CEntre de Recherche et d'Innovation en Audiologie Humain
- Study coordinator: Marta Campi, PhD
- Email: marta.campi@pasteur.fr
- Phone: ++33 (0) 1 76 53 51 12
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.