Improving healing and quality of life in patients with combined endodontic and periodontal lesions
"Role of Guided Tissue Regeneration on Healing Outcome & Quality of Life in Combined Endo Perio Lesions With Communication: A Randomized Controlled Trial"
This study is testing a new dental treatment that combines two techniques to see if it helps patients with specific gum and tooth issues heal better and feel happier after surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 16 Years and up |
| Sex | All |
| Sponsor | Postgraduate Institute of Dental Sciences Rohtak Academic / other |
| Locations | 1 site (Haryāna) |
| Trial ID | NCT06643663 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of combining PRF-Medium plug and ACM membrane in treating apico-marginal defects with interproximal involvement compared to conventional endodontic surgery techniques. It aims to assess healing outcomes using 2D periapical radiographs and 3D CBCT imaging, as well as evaluate the quality of life of patients post-surgery. The study includes patients aged 16 and above with specific dental conditions and excludes those with certain complications. The goal is to determine if the new approach leads to better recovery and improved patient satisfaction.
Who should consider this trial
Good fit: Ideal candidates are patients aged 16 and older with non-vital teeth and chronic apical periodontitis involving apico-marginal defects.
Not a fit: Patients with vertical root fractures, root perforations, or those classified as ASA-3 or ASA-4 will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly enhance healing outcomes and quality of life for patients with complex dental issues.
How similar studies have performed: Previous studies have shown promising results with guided tissue regeneration techniques, but this specific combination of PRF-Medium and ACM membrane is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients of age 16yrs and above. 2. Patients with apico-marginal defects and deep pocket upto apex of tooth. 3. Failed primary root canal treatment. 4. Presence of interproximal bone loss. 5. Negative response to vitality test. 6. ASA-1 or ASA- 2 according to the classification of the American Society of Anesthesiologists) Exclusion criteria: 1. Presence of vertical root fracture 2. Presence of root perforations 3. ASA-3 or ASA-4 according to the classification of the American Society of Anesthesiologists) 4. Presence of root resorption 5. Combined endodontic-periodontic lesions. 6. Pregnancy
Where this trial is running
Haryāna
- Pgids Rohtak — Haryāna, India (Recruiting)
Study contacts
- Study coordinator: Dr. Shweta Mittal, MDS
- Email: shwetagoelendo@gmail.com
- Phone: 9255596960
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.