Improving gut bacteria through enteral feeding after bowel surgery
Does Distal Enteral Feeding of Fibre Positively Affect the Microflora in the Distal Limb of Loop Ileostomy Patients?
NA · Lancashire Teaching Hospitals NHS Foundation Trust · NCT06288464
This study is testing if feeding patients through a tube after bowel surgery can help restore healthy gut bacteria and reduce complications during their recovery.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 15 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Lancashire Teaching Hospitals NHS Foundation Trust (other) |
| Locations | 1 site (Preston, Lancashire) |
| Trial ID | NCT06288464 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of enteral feeding on gut microbiota in patients who have undergone bowel surgery and are at risk of complications during reversal surgery. Patients will receive a nutrition shake through a feeding tube into the defunctioned part of the stoma, gradually increasing the volume over four weeks, with the addition of soluble fiber in the final week. The goal is to replenish beneficial bacteria in the bowel to reduce post-operative complications. This pilot study will inform a larger randomized controlled trial in the future.
Who should consider this trial
Good fit: Ideal candidates are individuals scheduled for ileostomy or colostomy reversal surgery who can provide informed consent.
Not a fit: Patients who are not undergoing ileostomy or colostomy reversal will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce post-operative complications for patients undergoing bowel surgery.
How similar studies have performed: While there is existing research on gut microbiota and post-operative outcomes, this specific approach of enteral feeding with fiber is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Any individual that has been identified for distal (stoma) feeding that is able to understand verbal and written English to provide informed consent. * Participants must be undergoing ileostomy or colostomy reversal surgery. Exclusion Criteria: * Not undergoing ileostomy or colostomy reversal. * Persons who might not adequately understand verbal explanations or written information given in English
Where this trial is running
Preston, Lancashire
- Lancashire Teaching Hospitals NHS — Preston, Lancashire, United Kingdom (RECRUITING)
Study contacts
- Study coordinator: Kina Bennett
- Email: kina.bennett@lthtr.nhs.uk
- Phone: (+44) 01772 522031
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Bowel Dysfunction, Colon Disease, Ileum--Diseases