Improving gut bacteria through enteral feeding after bowel surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of enteral feeding on gut microbiota in patients who have undergone bowel surgery and are at risk of complications during reversal surgery. Patients will receive a nutrition shake through a feeding tube into the defunctioned part of the stoma, gradually increasing the volume over four weeks, with the addition of soluble fiber in the final week. The goal is to replenish beneficial bacteria in the bowel to reduce post-operative complications. This pilot study will inform a larger randomized controlled trial in the future.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Any individual that has been identified for distal (stoma) feeding that is able to understand verbal and written English to provide informed consent.
* Participants must be undergoing ileostomy or colostomy reversal surgery.

Exclusion Criteria:

* Not undergoing ileostomy or colostomy reversal.
* Persons who might not adequately understand verbal explanations or written information given in English

Where it's running

• Lancashire Teaching Hospitals NHS
  Preston, Lancashire, United Kingdom Recruiting

Study contacts

• Study coordinator: Kina Bennett
• Email: kina.bennett@lthtr.nhs.uk
• Phone: (+44) 01772 522031

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Liquid biopsy and machine learning to detect early colorectal cancer, advanced adenomas, Lynch-related cancers, and residual disease

  This project will test a blood-based liquid biopsy that uses microRNA signals and machine learning to detect colorectal cancer, advanced adenomas, Lynch-associated cancers, and molecular residual disease in people who have a colonoscopy.

  Recruiting San Raffaele University · Milan, Lombardy and 3 other locations · NCT07450612

• Evaluating bowel preparation and colonoscopy safety in patients with chronic diseases

  This study is testing how safe and effective bowel preparation and colonoscopy are for adults with chronic heart, kidney, or liver diseases.

  Recruiting Asian Institute of Gastroenterology, India · Hyderabad, Telangana · NCT06874036

• Noninvasive spinal cord stimulation for recovery after spinal cord injury

  This study is testing a new non-invasive treatment to see if it can help improve bladder, bowel, sexual, and heart functions in people who have had a spinal cord injury for a few months.

  Recruiting University of British Columbia · Vancouver, British Columbia · NCT06587841

• Research on gut inflammation in pediatric patients with inflammatory bowel diseases

  This study is trying to learn more about gut inflammation in kids with inflammatory bowel diseases by collecting health information and samples from them and comparing it to kids who have different gut issues but no inflammation.

  Recruiting Seattle Children's Hospital · Seattle, Washington · NCT06315179

• Comparing non-operative management of acute diverticulitis in medical vs surgical wards

  This study looks at how well non-surgical treatment for acute diverticulitis works for patients in medical versus surgical hospital wards.

  Recruiting Ospedali Riuniti Trieste · Trieste, TS · NCT06265649

• Comparing bowel cleansing agents Plenvu and Picoprep before colonoscopy

  This study is testing whether Plenvu or Picoprep works better and is easier to handle for people getting ready for a colonoscopy.

  Recruiting Phase 4 Aalborg University Hospital · Aalborg, North Jutland · NCT05436054

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.