Improving finger joint motion with exercise orthoses

Effectiveness of Exercise Relative Motion Orthoses for Improving Limited Proximal Phalangeal Joint Motion: A Single-Center, Single-Blinded Randomized Controlled Trial

NA · Insel Gruppe AG, University Hospital Bern · NCT06985459

This study is testing if two types of exercise braces can help people with stiff finger joints move better after hand injuries.

Quick facts

PhaseNA
Study typeInterventional
Enrollment148 (estimated)
Ages18 Years and up
SexAll
SponsorInsel Gruppe AG, University Hospital Bern (other)
Locations1 site (Bern, Canton of Bern)
Trial IDNCT06985459 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of two types of exercise orthoses, the Relative Motion Flexion (RMF) and Relative Motion Extension (RME), in enhancing motion for patients with proximal interphalangeal joint stiffness. A total of 148 adult patients with acute hand injuries and a significant difference between active and passive joint motion will be enrolled and randomized to receive either the exercise orthosis or a placebo. Participants will wear the orthosis for four weeks while continuing standard hand therapy, with follow-up assessments to measure range of motion and patient satisfaction. The study aims to determine if these innovative orthoses can improve joint mobility during daily activities.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years with acute proximal interphalangeal joint motion deficits of at least 10°.

Not a fit: Patients with previous hand injuries or conditions like osteoarthritis that affect joint mobility may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly enhance the range of motion and functional ability of patients with finger joint stiffness.

How similar studies have performed: Previous studies have shown positive outcomes with similar exercise-based orthoses, indicating potential for success in this trial.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* PIPJ motion deficit with a minimum difference of 10° between passive and active motion
* To have an acute injury, i.e. operated on or within maximum 6 weeks of accident
* Only one hand is affected
* Adult patients over 18 years of age
* Understanding German, French or English
* Hand therapy treatment in-house at Inselspital in Bern
* Ability to give informed consent as documented by signature

Exclusion Criteria:

* Previous injuries to the hand or PIPJ (e.g., intra-articular fractures, PIPJ ligament damage) that may limit baseline joint mobility and influence responsiveness to the intervention.
* Presence of conditions such as osteoarthritis (OA) or rheumatoid arthritis (RA) that may affect PIPJ stiffness, pain, or inflammation.
* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia
* Boutonniere deformity
* Minors (below 18 years of age)

Where this trial is running

Bern, Canton of Bern

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Proximal Interphalangeal Joint Stiffness, Proximal Interphalangeal Joint, Limited Range of Motion, Exercise Relative Motion Orthosis, Randomized Controlled Trial

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.