Improving end-of-life care for patients with hematological diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on enhancing end-of-life care for patients diagnosed with hematological cancers, such as multiple myeloma and acute myeloid leukemia. It employs a novel approach called 'Advance Consultations Concerning participants Life and Treatment' (ACT), which aims to improve communication between patients, their caregivers, and healthcare providers regarding prognosis and treatment options. The intervention seeks to reduce unnecessary treatments and improve the quality of life for patients nearing the end of life. Participants will engage in consultations that emphasize palliative care and informed decision-making.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patients must:

* Be at least 18 years of age
* Have a diagnosis of one of the following:
* High-risk myelodysplastic syndrome (MDS) or MDS with overlap of myeloproliferative neoplasms (high-risk MDS/MPN),
* Acute myeloid leukemia(AML): Age≥80 or in palliative treatment or relapse
* Lymphoma: Age≥80 or relapse or refractory or palliative treatment
* Multiple myeloma(MM): Age≥80 or relapsed or refractory

Have limited treatment options. Provide informed consent. Have sufficient Danish skills to complete intervention sessions and data collection

An informal caregiver is identified by the patient as the primary provider of informal physical, practical or emotional support and must:

* Be at least 18 years of age
* Be able to accompany patients to intervention appointments
* Provide informed consent
* Have sufficient Danish skills to complete intervention sessions and data collection

Physicians:

* specialized in hematology
* treating patients with High risk myelodysplastic syndrome, acute myeloid leukemia, lymphoma, or multiple myeloma
* work at the same department for the entire time of intervention.

Nurses:

* treating patients with High-risk myelodysplastic syndrome, acute myeloid leukemia, lymphoma, or multiple myeloma
* work at the same department for the entire time of intervention.

Exclusion Criteria:

Patient and caregiver are excluded if one of them is:

\- Suffering from a severe psychiatric disorder

Physicians and nurses:

\- If they do not meet the inclusion criterion.

Where it's running

• Aalborg Universitetshospital
  Aalborg, Denmark Recruiting
• Aarhus Universitetshospital
  Aarhus, Denmark Recruiting
• Sydvestjysk sygehus - Esbjerg
  Esbjerg, Denmark Recruiting
• Regionshospitalet Gødstrup
  Herning, Denmark Recruiting
• Odense Universitetshospital
  Odense, Denmark Recruiting
• Sjællands universitetshospital Roskilde
  Roskilde, Denmark Recruiting

Study contacts

• Principal investigator: Christoffer Johansen, Professor — Copenhagen University Hospital, Rigshospitalet
• Study coordinator: Cæcilie Borregaard Myrhøj, MScN
• Email: caecilie.borregaard.myrhoej@regionh.dk
• Phone: +45 60701620

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.