Improving early lung cancer detection in diverse populations
Improving Detection of Early Lung Cancer in a Diverse Population
This study is trying to find a new way to spot lung cancer early in people who aren't eligible for regular screenings by using breath samples and blood tests to tell the difference between cancerous and non-cancerous growths.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 3600 (estimated) |
| Ages | 50 Years to 80 Years |
| Sex | All |
| Sponsor | British Columbia Cancer Agency Academic / other |
| Locations | 1 site (Vancouver, British Columbia) |
| Trial ID | NCT06628102 on ClinicalTrials.gov |
What this trial studies
This trial aims to identify high-risk individuals for lung cancer who currently do not qualify for low-dose computed tomography (LDCT) screening. It will also establish a framework for managing patients with incidental pulmonary nodules (IPNs) through accurate interpretation of existing chest CT scans. Additionally, the study seeks to develop a minimally invasive test using breath samples and blood proteins to differentiate between cancerous and non-cancerous nodules. Participants will provide demographic and health-related information to aid in the assessment.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 50-80 with a chest CT showing a nodule of 6mm or larger and who have not smoked in the last 24 hours.
Not a fit: Patients who are too sick to provide a breath sample, pregnant, or have a recent respiratory infection may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to earlier detection of lung cancer in patients who are currently overlooked, potentially saving lives.
How similar studies have performed: Other studies have shown promise in using similar approaches for lung cancer detection, but this specific methodology is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Age 50-80 * Able to consent * Chest CT positive for nodule equal to or greater than 6mm * No additional other cancer- (outside of lung cancer for group 1) * Must be able to abstain from smoking tobacco for 24 hours prior to the breath test. Exclusion Criteria: * Too sick to provide a breath sample * you have smoked in the last 24 hours * You are pregnant * You have been diagnosed with a respiratory infection in the last 3 months * Unwilling to consent to the study
Where this trial is running
Vancouver, British Columbia
- BC Cancer Research, part of the Provincial Health Authority — Vancouver, British Columbia, Canada (Recruiting)
Study contacts
- Principal investigator: Renelle L Myers, MD — Vch, Ubc
- Study coordinator: Renelle L Myers, MD
- Email: renelle.myers@vch.ca
- Phone: 6046758096
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.