Improving diagnosis of fungal sinusitis in ENT patients
Official title: Diagnostics of Mycotic Sinusitis in Patients With Unilateral Obfuscation of the Paranasal Sinus and Patients With Uni-lateral Discharge From the Nasal Cavity
Run by University Hospital Ostrava · NCT05955859 · Data updated 2026-11-12
This study is testing new ways to better diagnose fungal sinusitis in patients with sinus issues by using different examinations and imaging techniques.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 65 (estimated) |
| Sponsor | University Hospital Ostrava Academic / other |
| Locations | 1 site (Ostrava, Czech Republic) |
| Status | Recruiting |
| Started | May 2, 2023 |
| Main results expected | December 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | July 27, 2023 |
| Trial ID | NCT05955859 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older with unilateral obstruction and discharge from the paranasal sinus.
✕Probably not a fit
Patients with serious illnesses, psychiatric conditions, or those who are pregnant may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to enhance the diagnostic process for mycotic sinusitis, a rare inflammatory condition affecting the paranasal sinuses. Patients will undergo a thorough evaluation, including ENT examinations, rhinological questionnaires, endoscopic assessments, and CT imaging of the sinuses. The goal is to identify specific signs that can aid in the accurate diagnosis of fungal sinusitis, which is often challenging due to its nonspecific symptoms. Additionally, functional endonasal endoscopic surgery may be performed to sample affected sinus tissue.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and timely diagnoses of fungal sinusitis, improving patient outcomes.
How similar studies have gone: While the approach to diagnosing fungal sinusitis is critical, similar studies have not been widely reported, making this an important and potentially novel investigation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age ≥ 18 years * patients with unilateral obfuscation of the paranasal sinus and patients with unilateral discharge from the nasal cavity Exclusion Criteria: * serious illness (decompensation phase) - cardiac, liver, kidney disease, can-cer * serious psychiatric illnesses * pregnancy * high operative risk according to The American Society of Anesthesiologists (ASA) ≥ IV * disagreement with participation in the study
Where it's running
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University Hospital Ostrava, Department of Otorhinolaryngology and Head and Neck Surgery
Ostrava, Czech Republic, Czechia Recruiting
Study contacts
- Principal investigator: Simona Polášková, MD — University Hospital Ostrava
- Study coordinator: Jiří Hynčica
- Email: jiri.hyncica@fno.cz
- Phone: 0042059737
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.