Improving diagnosis of complex eye infections

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates new techniques to enhance the microbiological diagnosis of complex ocular infections, specifically endophthalmitis and corneal abscesses. It utilizes advanced molecular tools such as metagenomic sequencing for endophthalmitis and multiplex polymerase chain reaction for corneal abscesses. The goal is to determine the impact and accuracy of these methods in identifying the causative pathogens in these infections, which are often challenging to diagnose due to sample volume limitations and the complexity of the ocular site.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patient
* Patient presenting or having presented a clinical suspicion of complex ocular infection requiring a sample for microbiological diagnosis:

  * Corneal abscess requiring hospitalization
  * Any suspicion of endogenous or exogenous endophthalmitis.
* Patient not opposed to participating in the research

Exclusion Criteria:

* Patient under guardianship or curatorship
* Pregnant women

Where it's running

• Equipe mobile d'infectiologie, Cochin hospital
  Paris, Idf, France Recruiting

Study contacts

• Principal investigator: Etienne CANOUI, MD — Assistance Publique - Hôpitaux de Paris
• Study coordinator: Etienne CANOUI, MD
• Email: etienne.canoui@aphp.fr
• Phone: 0033158414267

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.