Improving diagnosis and treatment of mediastinal diseases using ultrasound techniques

Application Value of Respiratory Mediastinal Intervention Technique in Diagnosis and Comprehensive Treatment of Diseases

Observational Tianjin Medical University General Hospital · NCT06128681

This study is testing a new ultrasound technique to see if it helps doctors diagnose and treat mediastinal diseases better than the usual methods.

Quick facts

Study typeObservational
Enrollment30 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorTianjin Medical University General Hospital Academic / other
Locations1 site (Tianjin)
Trial IDNCT06128681 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the effectiveness of intrapacial ultrasound-guided mediastinal opening techniques for diagnosing and treating mediastinal diseases. It will compare outcomes between patients undergoing this innovative technique and those receiving standard care. The study focuses on determining whether this approach provides greater clinical benefits, particularly in the diagnosis of benign versus malignant conditions and in the ablation of mediastinal masses. Participants will undergo procedures that may include biopsies and various ablation methods such as freezing or laser treatment.

Who should consider this trial

Good fit: Ideal candidates are patients with radiographic abnormalities in the mediastinum who can tolerate general anesthesia and bronchoscopy.

Not a fit: Patients who have definitive diagnoses from imaging or tests, or those unable to tolerate anesthesia or sign consent forms, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic accuracy and treatment outcomes for patients with mediastinal diseases.

How similar studies have performed: While this approach is innovative, similar studies using ultrasound-guided techniques have shown promise in other areas of medicine, suggesting potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Radiographic abnormalities of mediastinum
* Can tolerate general anesthesia
* Can tolerate bronchoscopy and has the condition to have mediastinal biopsy and treatment

Exclusion Criteria:

* Imaging or other tests can make a definitive diagnosis
* Cannot tolerate general anesthesia or tracheoscopic surgery
* Patients cannot sign informed consent forms

Where this trial is running

Tianjin

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Mediastinal Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.