Clinical trial Recruiting at 1 site Observational Ages 18 to 80

Improving diagnosis and treatment of mediastinal diseases using ultrasound techniques

Official title: Application Value of Respiratory Mediastinal Intervention Technique in Diagnosis and Comprehensive Treatment of Diseases

Run by Tianjin Medical University General Hospital · NCT06128681 · Data updated 2026-11-12

This study is testing a new ultrasound technique to see if it helps doctors diagnose and treat mediastinal diseases better than the usual methods.

Quick facts

Study typeObservational
Ages18 Years to 80 Years
SexAll
Enrollment30 (estimated)
SponsorTianjin Medical University General Hospital
Academic / other
Locations1 site (Tianjin)
StatusRecruiting
StartedDecember 1, 2021
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedFebruary 10, 2026
Trial IDNCT06128681 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients with radiographic abnormalities in the mediastinum who can tolerate general anesthesia and bronchoscopy.

Probably not a fit

Patients who have definitive diagnoses from imaging or tests, or those unable to tolerate anesthesia or sign consent forms, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the effectiveness of intrapacial ultrasound-guided mediastinal opening techniques for diagnosing and treating mediastinal diseases. It will compare outcomes between patients undergoing this innovative technique and those receiving standard care. The study focuses on determining whether this approach provides greater clinical benefits, particularly in the diagnosis of benign versus malignant conditions and in the ablation of mediastinal masses. Participants will undergo procedures that may include biopsies and various ablation methods such as freezing or laser treatment.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic accuracy and treatment outcomes for patients with mediastinal diseases.

How similar studies have gone: While this approach is innovative, similar studies using ultrasound-guided techniques have shown promise in other areas of medicine, suggesting potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Radiographic abnormalities of mediastinum
* Can tolerate general anesthesia
* Can tolerate bronchoscopy and has the condition to have mediastinal biopsy and treatment

Exclusion Criteria:

* Imaging or other tests can make a definitive diagnosis
* Cannot tolerate general anesthesia or tracheoscopic surgery
* Patients cannot sign informed consent forms

Where it's running

  • Tianjin Medical University General Hospital
    Tianjin, China
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.