Improving detection of lymph node involvement in breast cancer using advanced imaging techniques

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to enhance the accuracy of detecting lymph node metastases in breast cancer patients by employing an integrative multidata approach (IMA) that combines clinical and laboratory data with multiparametric MRI. The study focuses on patients diagnosed with breast cancer who have undergone MRI and biopsy or surgery of axillary lymph nodes. By analyzing longitudinal imaging data, the study seeks to address the limitations of current methods, such as sentinel lymph node biopsy, which often yield negative results. The primary goal is to improve staging and treatment planning for breast cancer patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients diagnosed with breast cancer who underwent MRI and biopsy or surgery of axillary lymph nodes as part of their diagnosis and treatment
* Patients of all genders, ages, and stage I-III of breast cancer
* Patients who underwent neoadjuvant therapy and have longitudinal imaging data available for analysis (for secondary outcome analysis)

Exclusion Criteria:

* Patients whose MRI images were of insufficient quality for analysis
* Patients who had a previous history of breast cancer
* Patients with a history of axillary surgery or lymph node dissection prior to the current diagnosis of breast cancer
* Patients who received neoadjuvant therapy at another institution

Where it's running

• Landeskrankenhaus Villach
  Villach, Austria Recruiting
• KI4LIFE, Fraunhofer Austria Research
  Austria, Austria, Italy Recruiting
• Klinikum Klagenfurt am Wörthersee Klagenfurt am Wörthersee
  Villach, Austria, Italy Recruiting
• Centro di Riferimento Oncologico
  Aviano, Pordenone, Italy Recruiting

Study contacts

• Study coordinator: Fabio Del Ben, PhD
• Email: fabio.delben@cro.it
• Phone: 0434659101

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.