Improving depression in midlife Korean American women using a web app
Official title: A Web-App Based Lifestyle Physical Activity Promotion Program to Improve Depressive Symptom Experience: Midlife Korean American Women
Run by Vanderbilt University · NCT05405803 · Data updated 2026-11-12
This study tests if a web app that encourages physical activity can help improve depression in midlife Korean American women who are feeling down.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years to 60 Years |
| Sex | Women only |
| Enrollment | 300 (estimated) |
| Sponsor | Vanderbilt University Academic / other |
| Locations | 1 site (Nashville, Tennessee) |
| Status | Recruiting |
| Started | December 12, 2022 |
| Main results expected | June 2027 |
| Study ends | January 2028 |
| Registry record updated | October 30, 2026 |
| Trial ID | NCT05405803 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are self-reported midlife Korean American women aged 40 to 60 who are sedentary and have experienced depressive symptoms.
✕Probably not a fit
Patients with major cardiovascular issues or those on specific medications that affect physical activity may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of a web app-based Lifestyle Physical Activity Promotion Program aimed at improving depressive symptoms in midlife Korean American women. The program provides information and coaching to encourage increased physical activity, which may alleviate depressive symptoms associated with menopause and cultural factors. Participants will be midlife Korean American women aged 40 to 60 who are sedentary and have experienced depressive symptoms recently. The study seeks to determine if this intervention can lead to significant improvements in their mental health.
Why it matters
Potential benefit: If successful, this program could provide a valuable tool for midlife Korean American women to manage and reduce depressive symptoms through increased physical activity.
How similar studies have gone: Other studies have shown positive outcomes with web-based interventions for depression, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * self-reported midlife Korean-American women * aged 40 to 60 years * whose parents and grandparents are of Korean descent; * who can read and write English or Korean; * who currently reside in the United States; * who are sedentary (without any disabilities preventing physical activity); * who are online through computers or mobile devices; * have experienced depressive symptoms during the past two weeks (1 to 10 on the Patient Health Questionnaire \[PHQ-9\],which is equivalent to the cut-point of minimal to moderate depression. Exclusion Criteria: * major signs or symptoms suggestive of pulmonary or CVD * history of a myocardial infarction, stroke, or Type I diabetes mellitus * blood pressure higher than 160/100 mm Hg * Use of beta-blockers, diltiazem, or verapamil
Where it's running
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Vanderbilt University
Nashville, Tennessee, United States Recruiting
Study contacts
- Principal investigator: Eun-Ok Im, PhD, MPH — Vanderbilt University
- Study coordinator: Wonshik Chee, PhD
- Email: wpapp.help@vanderbilt.edu
- Phone: 615-343-4671
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.