Improving decannulation time in tracheostomized patients through inspiratory muscle training

Assessment of the Effect of an Inspiratory Muscle Training Regimen on Decannulation Time in Adult Hospitalized Subjects with Tracheostomy Secondary to Prolonged Mechanical Ventilation

Not applicable Interventional Hospital Dr. Franco Ravera Zunino · NCT06684392

This study is testing if a special breathing exercise program can help patients with tracheostomies get off their breathing tubes faster than those who only receive regular therapy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment56 (estimated)
Ages18 Years and up
SexAll
SponsorHospital Dr. Franco Ravera Zunino Academic / other
Locations1 site (Rancagua, Región del Libertador General Bernardo O’Higgins)
Trial IDNCT06684392 on ClinicalTrials.gov

What this trial studies

This project evaluates the impact of an individualized inspiratory muscle training regimen on decannulation time in patients with tracheostomy due to prolonged mechanical ventilation. Over a two-week period, participants will engage in strength and endurance exercises aimed at enhancing respiratory muscle performance. The study compares an experimental group receiving this training alongside standard physiotherapy to a control group receiving only standard physiotherapy. Key outcomes include decannulation time, ICU length of stay, hospital days, and quality of life scores, with the goal of optimizing management for tracheostomized patients.

Who should consider this trial

Good fit: Ideal candidates are critically ill adults aged 18 and older who are connected to mechanical ventilation and have undergone tracheostomy due to prolonged ventilation.

Not a fit: Patients with degenerative neuromuscular diseases or those who refuse to participate will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce the time patients remain on tracheostomy, improving their recovery and quality of life.

How similar studies have performed: While the concept of inspiratory muscle training is recognized, this specific individualized approach has not been widely tested, making it a novel intervention.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Critically ill patients aged ≥ 18 years
* Connected to mechanical ventilation
* Secondary tracheostomy due to prolonged mechanical ventilation
* Glasgow Coma Scale (GCS) \> 11 points
* Level of cooperation score (S5Q) \> 3 points

Exclusion Criteria:

* Limitation of therapeutic effort (LTE\*)
* Pregnancy
* Transfer to another center before completing the training (2 weeks)
* Degenerative neuromuscular disease
* Refusal to participate in this study (declining to provide informed consent \[IC\]).

Where this trial is running

Rancagua, Región del Libertador General Bernardo O’Higgins

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Tracheostomy ComplicationDiaphragm Diseasetracheostomyinspiratory muscle trainingdiaphragm dysfunctiondiaphragm ultrasound
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.